Controversies in epilepsy: Debates held during the Fourth International Workshop on Seizure Prediction

被引:56
作者
Frei, Mark G. [1 ]
Zaveri, Hitten P. [2 ]
Arthurs, Susan [3 ]
Bergey, Gregory K. [4 ]
Jouny, Christophe C. [4 ]
Lehnertz, Klaus [5 ]
Gotman, Jean [6 ]
Osorio, Ivan [1 ,7 ]
Netoff, Theoden I. [8 ]
Freeman, Walter J. [9 ]
Jefferys, John [10 ]
Worrell, Gregory [11 ]
Le Van Quyen, Michel [12 ]
Schiff, Steven J. [13 ]
Mormann, Florian [5 ,14 ]
机构
[1] Flint Hills Sci LLC, Lawrence, KS USA
[2] Yale Univ, New Haven, CT USA
[3] Alliance Epilepsy Res, Dexter, MI USA
[4] Johns Hopkins Univ, Baltimore, MD USA
[5] Univ Bonn, D-5300 Bonn, Germany
[6] McGill Univ, Montreal Neurol Inst, Montreal, PQ, Canada
[7] Univ Kansas, Med Ctr, Kansas City, KS 66103 USA
[8] Univ Minnesota, Minneapolis, MN USA
[9] Univ Calif Berkeley, Berkeley, CA 94720 USA
[10] Univ Birmingham, Birmingham, W Midlands, England
[11] Mayo Clin, Rochester, MN USA
[12] Ctr Rech Inst Cerveau & Moelle Epiniere CRICM, Paris, France
[13] Penn State Univ, University Pk, PA 16802 USA
[14] CALTECH, Pasadena, CA 91125 USA
关键词
Seizure focus; Seizure onset area; Network; Interictal activity; Spikes; Ictogenesis; Inhibition; Excitation; Hyposynchrony; Hypersynchrony; High-frequency activity; High-frequency oscillations; Phase synchronization; HIGH-FREQUENCY OSCILLATIONS; TEMPORAL-LOBE EPILEPSY; IN-VITRO; PHASE SYNCHRONIZATION; INTERICTAL ACTIVITY; NEURONAL SYNCHRONY; INTRACRANIAL EEG; LIMBIC NETWORKS; NEURAL-NETWORKS; BRAIN NETWORKS;
D O I
10.1016/j.yebeh.2010.06.009
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Debates on six controversial topics were held during the Fourth International Workshop on Seizure Prediction (IWSP4) convened in Kansas City, KS, USA, July 4-7, 2009. The topics were (1) Ictogenesis: Focus versus Network? (2) Spikes and Seizures: Step-relatives or Siblings? (3) Ictogenesis: A Result of Hyposynchrony? (4) Can Focal Seizures Be Caused by Excessive Inhibition? (5) Do High-Frequency Oscillations Provide Relevant Independent Information? (6) Phase Synchronization: Is It Worthwhile as Measured? This article, written by the IWSP4 organizing committee and the debaters, summarizes the arguments presented during the debates. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码:4 / 16
页数:13
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