A probably isolated subclavicular lymphadenopathy in acute leukemia: An unusual localisation of cryptococcosis

被引：2

作者：

Harrabi, H. ^{[1
]}

Medhaffar, M. ^{[1
]}

Kammoun, L. ^{[1
]}

Maaloul, I. ^{[2
]}

Ayadi, L. ^{[3
]}

Elloumi, M. ^{[1
]}

机构：

[1] Hop Hedi Chaker, Dept Hematol, Sfax 3024, Tunisia

[2] Hop Hedi Chaker, Dept Infect Dis, Sfax 3024, Tunisia

[3] Hop Habib Bourguiba, Pathol Lab, Sfax 3024, Tunisia

来源：

JOURNAL DE MYCOLOGIE MEDICALE | 2010年 / 20卷 / 03期

关键词：

Cryptococcus neoformans; Lymphadenopathy; Acute leukemia; Surgery; Fluconazole; Cryptococcosis; PRACTICE GUIDELINES; DISEASE; MENINGITIS; MANAGEMENT;

D O I：

10.1016/j.mycmed.2010.07.001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Introduction. - Cryptococcus neoformans (C. neoformans) is a fungal opportunistic pathogen which infects immunocompromised patients, especially those who are seropositive for the human immunodeficiency virus (HIV) and those with lymphoproliferative malignancies. Lungs and meninx are the most frequently involved sites, but isolated lymph nodes are less infected. Case report. - We report the observation of an 18-year-old-patient, receiving chemotherapy for a lymphoblastic acute leukemia, who developed an isolated subclavicular lymphadenopathy. The diagnosis of cryptococcal lymphadenitis was confirmed by fine needle aspiration cytology and biopsy. Surgery and fluconazole allowed a favourable. outcome. Conclusion. - Isolated cryptococcal lymphadenopathy is a rare complication that occurs in patients with hematological malignancies. The diagnosis is based on culture and/or fine needle aspiration cytology and/or biopsy. The prognosis is favourable with surgical treatment and antifungal therapy. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：227 / 230

页数：4

共 15 条

[1]

CHUN ZC, 2006, J PEDIATR SURG, V41, pE11

[2]

DROMER F, 2004, CRYPTOCOCCOSE EMC MA, P21

[3] Determinants of disease presentation and outcome during cryptococcosis:: The CryptoA/D study [J].