Ceftriaxone-induced acute reversible encephalopathy in a patient with enteric fever

被引:10
作者
Sharma, Neetu [1 ]
Batish, Sandeep [2 ]
Gupta, Anita [1 ]
机构
[1] Govt Med Coll, Dept Pharmacol, Patiala, Punjab, India
[2] Primary Hlth Ctr, Haryana Commiss Med Serv 1, Bhagal, Haryana, India
来源
INDIAN JOURNAL OF PHARMACOLOGY | 2012年 / 44卷 / 01期
关键词
Adverse drug reaction; ceftriaxone; encephalopathy; neurotoxicity; ADVERSE DRUG-REACTIONS; ANTIBIOTICS;
D O I
10.4103/0253-7613.91884
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Ceftriaxone is a commonly used, third-generation cephalosporin. Encephalopathy is a rare side effect of third-and fourth-generation cephalosporins. Renal failure and previous disease of the central nervous system predispose to this neurotoxicity. We describe a case of acute transient encephalopathy in a patient treated with ceftriaxone for enteric fever infection. Early detection of this complication is relevant given that stopping the drug usually reverts the neurological syndrome.
引用
收藏
页码:124 / 125
页数:2
相关论文
共 7 条
[1]   FACTORS PREDISPOSING TO SEIZURES IN SERIOUSLY ILL INFECTED PATIENTS RECEIVING ANTIBIOTICS - EXPERIENCE WITH IMIPENEM-CILASTATIN [J].
CALANDRA, G ;
LYDICK, E ;
CARRIGAN, J ;
WEISS, L ;
GUESS, H .
AMERICAN JOURNAL OF MEDICINE, 1988, 84 (05) :911-918
[2]   RELATIONSHIP BETWEEN STRUCTURE AND CONVULSANT PROPERTIES OF SOME BETA-LACTAM ANTIBIOTICS FOLLOWING INTRACEREBROVENTRICULAR MICROINJECTION IN RATS [J].
DESARRO, A ;
AMMENDOLA, D ;
ZAPPALA, M ;
GRASSO, S ;
DESARRO, GB .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :232-237
[3]   Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy [J].
Eggers, V ;
Fügener, K ;
Hein, OV ;
Rommelspacher, H ;
Heyes, MP ;
Kox, WJ ;
Spies, CD .
INTENSIVE CARE MEDICINE, 2004, 30 (08) :1544-1551
[4]   PREVENTABILITY AND SEVERITY ASSESSMENT IN REPORTING ADVERSE DRUG-REACTIONS [J].
HARTWIG, SC ;
SIEGEL, J ;
SCHNEIDER, PJ .
AMERICAN JOURNAL OF HOSPITAL PHARMACY, 1992, 49 (09) :2229-2232
[5]   Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure [J].
Martínez-Rodríguez, JE ;
Barriga, FJ ;
Santamaria, J ;
Iranzo, A ;
Pareja, JA ;
Revilla, M ;
dela Rosa, CR .
AMERICAN JOURNAL OF MEDICINE, 2001, 111 (02) :115-119
[6]   A METHOD FOR ESTIMATING THE PROBABILITY OF ADVERSE DRUG-REACTIONS [J].
NARANJO, CA ;
BUSTO, U ;
SELLERS, EM ;
SANDOR, P ;
RUIZ, I ;
ROBERTS, EA ;
JANECEK, E ;
DOMECQ, C ;
GREENBLATT, DJ .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (02) :239-245
[7]  
Roncon-Albuquerque R, 2009, NETH J MED, V67, P72