Reigning in regulatory T-cell function

被引：1
|
作者：
Konopacki, Catherine [1 ,2 ]
Plitas, George [1 ,2 ,3 ]
Rudensky, Alexander [1 ,2 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Howard Hughes Med Inst, New York, NY 10021 USA
[2] Mem Sloan Kettering Canc Ctr, Ludwig Ctr, Program Immunol, New York, NY 10021 USA
[3] Mem Sloan Kettering Canc Ctr, Dept Surg, Breast Canc Serv, New York, NY 10021 USA
来源：
NATURE BIOTECHNOLOGY | 2015年 / 33卷 / 07期
关键词：
TGF-BETA; DIFFERENTIATION; TGF-BETA-1; CANCER; GROWTH;
D O I：
10.1038/nbt.3285
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
An approach to inhibit the immune-suppressive function of regulatory T cells is demonstrated in a model of graft-versus-host disease.
引用
收藏
页码：718 / 719
页数：2
相关论文
共 50 条
  • [1] Reigning in regulatory T-cell function
    Catherine Konopacki
    George Plitas
    Alexander Rudensky
    Nature Biotechnology, 2015, 33 : 718 - 719
  • [2] Regulatory T-cell function in autoimmunity
    Garcia-Valladares, Ignacio
    Espinoza, Luis R.
    IMMUNOTHERAPY, 2010, 2 (04) : 441 - 442
  • [3] Regulatory T-cell function of adult T-cell leukemia/lymphoma cells
    Yano, Hiroki
    Ishida, Takashi
    Inagaki, Atsushi
    Ishii, Toshihiko
    Kusumoto, Shigeru
    Komatsu, Hirokazu
    Iida, Shinsuke
    Utsunomiya, Atae
    Ueda, Ryuzo
    INTERNATIONAL JOURNAL OF CANCER, 2007, 120 (09) : 2052 - 2057
  • [4] A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy
    Canavan, James B.
    Afzali, Behdad
    Scotta, Cristiano
    Fazekasova, Henrieta
    Edozie, Francis C.
    Macdonald, Thomas T.
    Hernandez-Fuentes, Maria P.
    Lombardi, Giovanna
    Lord, Graham M.
    BLOOD, 2012, 119 (08) : E57 - E66
  • [5] Metabolic control of regulatory T-cell function
    De Rosa, V.
    IMMUNOLOGY, 2014, 143 : 9 - 9
  • [6] THYMOSIN MODULATION OF REGULATORY T-CELL FUNCTION
    MUTCHNICK, MG
    PRIETO, JA
    SCHAFFNER, JA
    WELLER, FE
    CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 1982, 23 (03): : 626 - 633
  • [7] REGULATORY FUNCTION OF THYMUS IN T-CELL DEVELOPMENT
    TUFVESON, G
    JUHLIN, R
    ALM, GV
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1977, 6 (11) : 1197 - 1198
  • [8] IMPACT OF GLIOMAS ON REGULATORY T-CELL SURVIVAL AND FUNCTION
    Ahn, Brian
    Crane, Courtney
    Han, Seunggu J.
    Parsa, Andrew T.
    NEURO-ONCOLOGY, 2009, 11 (05) : 616 - 616
  • [9] Aging is Associated with Increased Regulatory T-cell Function
    Garg, S. K.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2014, 62 : S4 - S4
  • [10] Aging is associated with increased regulatory T-cell function
    Garg, Sanjay K.
    Delaney, Colin
    Toubai, Tomomi
    Ghosh, Amiya
    Reddy, Pavan
    Banerjee, Ruma
    Yung, Raymond
    AGING CELL, 2014, 13 (03): : 441 - 448
12345