Psychological distress and salivary cortisol covary within persons during pregnancy

被引：75

作者：

Giesbrecht, Gerald F. ^{[1
]}

Campbell, Tavis ^{[1
]}

Letourneau, Nicole ^{[2
]}

Kooistra, Libbe ^{[3
]}

Kaplan, Bonnie ^{[1
]}

机构：

[1] Univ Calgary, Calgary, AB T2N 1N4, Canada

[2] Univ New Brunswick, Fredericton, NB E3B 5A3, Canada

[3] Univ Groningen, NL-9700 AB Groningen, Netherlands

来源：

PSYCHONEUROENDOCRINOLOGY | 2012年 / 37卷 / 02期

关键词：

Pregnancy; Cortisol; Stress; Psychological distress; Anxiety; Depression; Ecological momentary assessment; Saliva; Diurnal; PSYCHOSOCIAL STRESS; MATERNAL CORTISOL; POSTNATAL DEPRESSION; MOMENTARY ASSESSMENT; PRENATAL EXPOSURE; DAILY EVENTS; MOOD STATES; RESPONSES; VALIDITY; ANXIETY;

D O I：

10.1016/j.psyneuen.2011.06.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The mechanisms whereby maternal stress during pregnancy exerts organizational effects on fetal development require elaboration. The aim of this study was to assess the plausibility of cortisol as a biological link between maternal psychological distress during pregnancy and fetal development. Previous research has resulted in equivocal findings for between-persons differences in stress and cortisol. Ecological momentary assessment was used to simultaneously assess mood and cortisol 5 times daily for 3 days in 83 women (gestational ages 6-37 weeks). Results from multilevel analysis indicated a robust within-person association between negative mood and cortisol. For each 1.0% increase in negative mood there was a corresponding 1.9% increase in cortisol. This association was unaffected by advancing gestational age. The results suggest that cortisol is a plausible biological mechanism for transducing the effects of maternal psychological distress during pregnancy to fetal development. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：270 / 279

页数：10

共 51 条

[1] Depression and anxiety during pregnancy:: A risk factor for obstetric, fetal and neonatal outcome?: A critical review of the literature [J].