Risk profile of breast cancer following atypical hyperplasia detected through organized screening

被引：15

作者：

Buckley, Elizabeth ^{[1
]}

Sullivan, Tom ^{[2
]}

Farshid, Gelareh ^{[3
]}

Hiller, Janet ^{[4
]}

Roder, David ^{[1
]}

机构：

[1] Univ S Australia, Sch Populat Hlth, Adelaide, SA 5001, Australia

[2] Univ Adelaide, Sch Populat Hlth, Adelaide, SA 5005, Australia

[3] BreastScreen SA, Wayville, SA 5034, Australia

[4] Swinburne Univ Technol, Sch Hlth Sci, Fac Hlth Arts & Design, Hawthorn, Vic 3122, Australia

来源：

BREAST | 2015年 / 24卷 / 03期

关键词：

Atypia; Survival analysis; Invasive breast cancer; Ductal carcinoma in-situ; Breast screening; Mammography; WOMEN; DISEASE; MAMMOGRAPHY; MORPHOLOGY; HISTORY; LESIONS; TESTS;

D O I：

10.1016/j.breast.2015.01.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Few population-based data are available indicating the breast cancer risk following detection of atypia within a breast screening program. Methods: Prospectively collected data from the South Australian screening program were linked with the state cancer registry. Absolute and relative breast cancer risk estimates were calculated for ADH and ALH separately, and by age at diagnosis and time since diagnosis. Post-hoc analysis was undertaken of the effect of family history on breast cancer risk. Results: Women with ADH and ALH had an increase in relative risk for malignancy (ADH HR 2.81 [95% CI 1.72, 4.59] and (ALH HR 4.14 [95% CI 1.97, 8.69], respectively. Differences in risk profile according to time since diagnosis and age at diagnosis were not statistically significant. Conclusion: Estimates of the relative risk of breast cancer are necessary to inform decisions regarding clinical management and/or treatment of women with ADH and ALH. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：208 / 212

页数：5

共 31 条

[1]

[Anonymous], 2011, AUSTR STAT GEOGR STA

[2]

[Anonymous], 2009, Breast cancer in Australia: an overview, 2009

[3]

[Anonymous], 2006, INTR SOC IND AR SEIF

[4]

BreastScreen SA, 2010, IMP BREASTSCREEN SA

[5] A PROSPECTIVE-STUDY OF THE DEVELOPMENT OF BREAST-CANCER IN 16,692 WOMEN WITH BENIGN BREAST DISEASE [J].

CARTER, CL ;

CORLE, DK ;

MICOZZI, MS ;

SCHATZKIN, A ;

TAYLOR, PR .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1988, 128 (03) :467-477

[6]

Clapton W, 2003, S HLTH DAT LINK ITS

[7] Magnitude and laterality of breast cancer risk according to histologic type of atypical hyperplasia - Results from the Nurses' Health Study [J].

Collins, Laura C. ;

Baer, Heather J. ;

Tamimi, Rulla M. ;

Connolly, James L. ;

Colditz, Graham A. ;

Schnitt, Stuart J. .

CANCER, 2007, 109 (02) :180-187

[8] The influence of family history on breast cancer risk in women with biopsy-confirmed benign breast disease - Results from the nurses' health study [J].

Collins, Laura C. ;

Baer, Heather J. ;

Tamimi, Rulla M. ;

Connolly, James L. ;

Colditz, Graham A. ;

Schnitt, Stuart J. .

CANCER, 2006, 107 (06) :1240-1247

[9] Stratification of breast cancer risk in women with atypia: A Mayo cohort study [J].

Degnim, Amy C. ;

Visscher, Daniel W. ;

Berman, Hal K. ;

Frost, Marlene H. ;

Sellers, Thomas A. ;

Vierkant, Robert A. ;

Maloney, Shaun D. ;

Pankratz, V. Shane ;

de Groen, Piet C. ;

Lingle, Wilma L. ;

Ghosh, Karthik ;

Penheiter, Lois ;

Tlsty, Thea ;

Melton, L. Joseph, III ;

Reynolds, Carol A. ;

Hartmann, Lynn C. .

JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (19) :2671-2677

[10] Correcting for non-compliance bias in case-control studies to evaluate cancer screening programmes [J].

Duffy, SW ;

Cuzick, J ;

Tabar, L ;

Vitak, B ;

Chen, THH ;

Yen, MF ;

Smith, RA .

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 2002, 51 :235-243

← 1 2 3 4 →