TRIM proteins and cancer

被引：669

作者：

Hatakeyama, Shigetsugu ^{[1
,2
]}

机构：

[1] Hokkaido Univ, Dept Biochem, Inst Anim Expt, Grad Sch Med,Kita Ku, Sapporo, Hokkaido 0608638, Japan

[2] Hokkaido Univ, Grad Sch Med, Cent Inst Isotope Sci, Kita Ku, Sapporo, Hokkaido 0608638, Japan

来源：

NATURE REVIEWS CANCER | 2011年 / 11卷 / 11期

关键词：

ACUTE PROMYELOCYTIC LEUKEMIA; CHRONIC LYMPHOCYTIC-LEUKEMIA; RET FINGER PROTEIN; ESTROGEN-RECEPTOR-ALPHA; TUMOR-SUPPRESSOR GENE; PML-RAR-ALPHA; LIGAND-DEPENDENT TRANSCRIPTION; TELANGIECTASIA GROUP-D; E3 UBIQUITIN LIGASE; RING FINGER;

D O I：

10.1038/nrc3139

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Emerging clinical evidence shows that the deregulation of ubiquitin-mediated degradation of oncogene products or tumour suppressors is likely to be involved in the aetiology of carcinomas and leukaemias. Recent studies have indicated that some members of the tripartite motif (TRIM) proteins (one of the subfamilies of the RING type E3 ubiquitin ligases) function as important regulators for carcinogenesis. This Review focuses on TRIM proteins that are involved in tumour development and progression.

引用

页码：792 / 804

页数：13

共 163 条

[1] THE PHD FINGER - IMPLICATIONS FOR CHROMATIN-MEDIATED TRANSCRIPTIONAL REGULATION
AASLAND, R
GIBSON, TJ
STEWART, AF
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1995, 20 (02) : 56 - 59
[2] Recruitment of TIF1γ to Chromatin via Its PHD Finger-Bromodomain Activates Its Ubiquitin Ligase and Transcriptional Repressor Activities
Agricola, Eleonora
Randall, Rebecca A.
Gaarenstroom, Tessa
Dupont, Sirio
Hill, Caroline S.
[J]. MOLECULAR CELL, 2011, 43 (01) : 85 - 96
[3] Trim24 targets endogenous p53 for degradation
Allton, Kendra
Jain, Abhinav K.
Herz, Hans-Martin
Tsai, Wen-Wei
Jung, Sung Yun
Qin, Jun
Bergmann, Andreas
Johnson, Randy L.
Barton, Michelle Craig
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (28) : 11612 - 11616
[4] IDENTIFICATION OF A NOVEL NUCLEAR DOMAIN
ASCOLI, CA
MAUL, GG
[J]. JOURNAL OF CELL BIOLOGY, 1991, 112 (05) : 785 - 795
[5] Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia
Aucagne, Romain
Droin, Nathalie
Paggetti, Jerome
Lagrange, Brice
Largeot, Anne
Hammann, Arlette
Bataille, Amandine
Martin, Laurent
Yan, Kai-Ping
Fenaux, Pierre
Losson, Regine
Solary, Eric
Bastie, Jean-Noel
Delva, Laurent
[J]. JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (06) : 2361 - 2370
[6] Distinct organization of the candidate tumor suppressor gene RFP2 in human and mouse:: multiple mRNA isoforms in both species- and human-specific antisense transcript RFP2OS
Baranova, A
Hammarsund, M
Ivanova, DV
Skoblov, M
Sangfelt, O
Corcoran, M
Borodina, T
Makeeva, N
Pestova, A
Tyazhelova, T
Nazarenko, S
Gorreta, F
Alsheddi, T
Schlauch, K
Nikitin, E
Kapanadze, B
Shagin, D
Poltaraus, A
Vorobiev, AI
Zabarovsky, E
Lukianov, S
Chandhoke, V
Ibbotson, R
Oscier, D
Einhorn, S
Grander, D
Yankovsky, N
[J]. GENE, 2003, 321 : 103 - 112
[7] Differentiation-specific association of HP1α and HP1β with chromocentres is correlated with clustering of TIF1β at these sites
Bartova, Eva
Pachernik, Jiri
Kozubik, Alois
Kozubek, Stanislav
[J]. HISTOCHEMISTRY AND CELL BIOLOGY, 2007, 127 (04) : 375 - 388
[8] 8pII myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFRI and TIFI genes
Belloni, E
Trubia, M
Gasparini, P
Micucci, C
Tapinassi, C
Confalonieri, S
Nuciforo, P
Martino, B
Lo-Coco, F
Pelicci, PG
Di Fiore, PP
[J]. GENES CHROMOSOMES & CANCER, 2005, 42 (03) : 320 - 325
[9] PML regulates p53 stability by sequestering Mdm2 to the nucleolus
Bernardi, R
Scaglioni, PP
Bergmann, S
Horn, HF
Vousden, KH
Pandolfi, PP
[J]. NATURE CELL BIOLOGY, 2004, 6 (07) : 665 - 672
[10] BERNSTEIN R, 1984, Cancer Genetics and Cytogenetics, V11, P300

← 1 2 3 4 5 6 7 8 9 10 →