Atrial fibrillation in a dish: insights into atrial arrhythmogenesis from induced pluripotent stem cell-derived cardiomyocytes

被引：0
作者：
Grandi, Eleonora [1 ]
Dobrev, Dobromir [2 ]
机构：
[1] Univ Calif Davis, Dept Pharmacol, 451 Hlth Sci Dr,Tupper Hall Rm 2427, Davis, CA 95616 USA
[2] Univ Duisburg Essen, West German Heart & Vasc Ctr, Inst Pharmacol, Hufelandstr 55, D-45122 Essen, Germany
来源：
CARDIOVASCULAR RESEARCH | 2020年 / 116卷 / 06期
基金：
美国国家卫生研究院;
关键词：
MECHANISMS;
D O I：
10.1093/cvr/cvz342
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1089 / 1091
页数：3
相关论文
共 14 条
[1]   The Clinical Profile and Pathophysiology of Atrial Fibrillation Relationships Among Clinical Features, Epidemiology, and Mechanisms [J].
Andrade, Jason ;
Khairy, Paul ;
Dobrev, Dobromir ;
Nattel, Stanley .
CIRCULATION RESEARCH, 2014, 114 (09) :1453-1468
[2]   Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes [J].
Benzoni, Patrizia ;
Campostrini, Giulia ;
Landi, Sara ;
Bertini, Valeria ;
Marchina, Eleonora ;
Iascone, Maria ;
Ahlberg, Gustav ;
Olesen, Morten Salling ;
Crescini, Elisabetta ;
Mora, Cristina ;
Bisleri, Gianluigi ;
Muneretto, Claudio ;
Ronca, Roberto ;
Presta, Marco ;
Poliani, Pier Luigi ;
Piovani, Giovanna ;
Verardi, Rosanna ;
Di Pasquale, Elisa ;
Consiglio, Antonella ;
Raya, Angel ;
Torre, Eleonora ;
Lodrini, Alessandra Maria ;
Milanesi, Raffaella ;
Rocchetti, Marcella ;
Baruscotti, Mirko ;
DiFrancesco, Dario ;
Memo, Maurizio ;
Barbuti, Andrea ;
Dell'Era, Patrizia .
CARDIOVASCULAR RESEARCH, 2020, 116 (06) :1147-1160
[3]   Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming [J].
Burridge, Paul W. ;
Keller, Gordon ;
Gold, Joseph D. ;
Wu, Joseph C. .
CELL STEM CELL, 2012, 10 (01) :16-28
[4]   Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes [J].
Cyganek, Lukas ;
Tiburcy, Malte ;
Sekeres, Karolina ;
Gerstenberg, Kathleen ;
Bohnenberger, Hanibal ;
Lenz, Christof ;
Henze, Sarah ;
Stauske, Michael ;
Salinas, Gabriela ;
Zimmermann, Wolfram-Hubertus ;
Hasenfuss, Gerd ;
Guan, Kaomei .
JCI INSIGHT, 2018, 3 (12)
[5]   EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: Definition, characterization, and clinical implication [J].
Goette, Andreas ;
Kalman, Jonathan M. ;
Aguinaga, Luis ;
Akar, Joseph ;
Angel Cabrera, Jose ;
Chen, Shih Ann ;
Chugh, Sumeet S. ;
Corradi, Domenico ;
D'Avila, Andre ;
Dobrev, Dobromir ;
Fenelon, Guilherme ;
Gonzalez, Mario ;
Hatem, Stephane N. ;
Helm, Robert ;
Hindricks, Gerhard ;
Ho, Siew Yen ;
Hoit, Brian ;
Jalife, Jose ;
Kim, Young-Hoon ;
Lip, Gregory Y. H. ;
Ma, Chang-Sheng ;
Marcus, Gregory M. ;
Murray, Katherine ;
Nogami, Akihiko ;
Sanders, Prashanthan ;
Uribe, William ;
van Wagoner, David R. ;
Nattel, Stanley .
HEART RHYTHM, 2017, 14 (01) :E3-E40
[6]   Translational Challenges in Atrial Fibrillation [J].
Heijman, Jordi ;
Guichard, Jean-Baptiste ;
Dobrev, Dobromir ;
Nattel, Stanley .
CIRCULATION RESEARCH, 2018, 122 (05) :752-773
[7]   The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis [J].
Heijman, Jordi ;
Algalarrondo, Vincent ;
Voigt, Niels ;
Melka, Jonathan ;
Wehrens, Xander H. T. ;
Dobrev, Dobromir ;
Nattel, Stanley .
CARDIOVASCULAR RESEARCH, 2016, 109 (04) :467-479
[8]   Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression [J].
Heijman, Jordi ;
Voigt, Niels ;
Nattel, Stanley ;
Dobrev, Dobromir .
CIRCULATION RESEARCH, 2014, 114 (09) :1483-1499
[9]   Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Insights Into Molecular, Cellular, and Functional Phenotypes [J].
Karakikes, Ioannis ;
Ameen, Mohamed ;
Termglinchan, Vittavat ;
Wu, Joseph C. .
CIRCULATION RESEARCH, 2015, 117 (01) :80-88
[10]   A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources [J].
Kernik, Divya C. ;
Morotti, Stefano ;
Wu, HaoDi ;
Garg, Priyanka ;
Duff, Henry J. ;
Kurokawa, Junko ;
Jalife, Jose ;
Wu, Joseph C. ;
Grandi, Eleonora ;
Clancy, Colleen E. .
JOURNAL OF PHYSIOLOGY-LONDON, 2019, 597 (17) :4533-4564
12