Fatal Aspergillosis of the Renal Vasculature in a Combined Liver-Kidney Transplant Recipient

被引：1

作者：

Nagvekar, Vasant ^{[1
]}

Pranatharthi, Chandrasekar H. ^{[7
]}

Gopalakrishnan, Ram ^{[2
]}

Anand, Ramamurthy ^{[3
]}

Devarajan, Vidya ^{[6
]}

Thirunarayan, Mandayam ^{[4
]}

Tarigopula, Anil ^{[5
]}

机构：

[1] Apollo Hosp, Dept Infect Dis, Madras, Tamil Nadu, India

[2] Apollo Hosp, Inst Infect Dis, Madras, Tamil Nadu, India

[3] Apollo Hosp, Dept Liver Transplant Surg, Madras, Tamil Nadu, India

[4] Apollo Hosp, Dept Microbiol, Madras, Tamil Nadu, India

[5] Apollo Hosp, Dept Mol Diagnost Lab & Transplantat Immunol, Madras, Tamil Nadu, India

[6] Apollo Canc Hosp, Dept Infect Dis, Madras, Tamil Nadu, India

[7] Wayne State Univ, Dept Med, Div Infect Dis, Detroit, MI 48202 USA

来源：

INDIAN JOURNAL OF MEDICAL MICROBIOLOGY | 2018年 / 36卷 / 03期

关键词：

Aspergillosis; kidney transplantation; perfusate; INVASIVE ASPERGILLOSIS; FUNGAL-INFECTIONS; RISK-FACTORS; DONOR;

D O I：

10.4103/ijmm.IJMM_18_165

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Invasive aspergillosis remains a problem in solid organs and haematopoietic stem cell transplants. We report a case of 12-year-old female with primary hyperoxaluria with regular haemodialysis for the end-stage renal disease. She underwent a combined liver and renal transplantation which got infected by aspergillosis. In this case study, it is speculated that the most likely source of Aspetgillus was contaminated preservative solution (perfusate), resulting in infection within the donor kidney and subsequent systemic infection in the recipient. This case study calls for critical analysis and needs for the routine culture of the preservative solution before transplantation, to detect any fungal contamination and manage it prophylactically.

引用

页码：444 / 446

页数：3

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