Ancestry informative markers derived from discriminant analysis of principal components provide important insights into the composition of crossbred cattle

被引:18
作者
Chhotaray, Supriya [1 ]
Panigrahi, Manjit [1 ]
Pal, Dhan [1 ]
Ahmad, Sheikh Firdous [1 ]
Bhushan, Bharat [1 ]
Gaur, G. K. [1 ]
Mishra, B. P. [2 ]
Singh, R. K. [2 ]
机构
[1] ICAR Indian Vet Res Inst, Div Anim Genet, Bareilly 243122, UP, India
[2] ICAR Indian Vet Res Inst, Div Vet Biotechnol, Bareilly 243122, UP, India
关键词
Ancestry informative markers; Breed composition; DAPC; Vrindavani; POPULATION-STRUCTURE; ADMIXTURE; IDENTIFICATION; ORIGIN; SNPS;
D O I
10.1016/j.ygeno.2019.10.008
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The cost of SNP genotyping to screen different breeds and to estimate the exact proportion of ancestry level is quite high, which can be compensated through deriving a small panel of ancestry informative markers (AIMs). Hence, we carried out the present study to provide an insight into ancestry level inferred from a panel of informative markers in the crossbred Vrindavani population developed at ICAR-IVRI, India. We have performed a new method i.e., discriminant analysis of principal components (DAPC) for the first time on the dataset of Vrindavani cattle. To confirm our method, we had performed DAPC on two other well-known crossbred cattle, i.e., Frieswal and Beefmaster. Three sets of panels (500, 1000 and 2000 markers) were tested for clustering of individuals. Among all the panels, we found the panel (1000 markers) with DAPC based contribution method was of the smallest size and comparatively of the highest accuracy.
引用
收藏
页码:1726 / 1733
页数:8
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