''Pseudodisappearance'' of atrial electrogram during orthodromic tachycardia: New criteria for successful ablation of concealed left-sided accessory pathways

被引:16
作者
Villacastin, J [1 ]
Almendral, J [1 ]
Medina, O [1 ]
Arenal, A [1 ]
Merino, JL [1 ]
Peinado, R [1 ]
MartinezAlday, J [1 ]
dePrado, AP [1 ]
Tercedor, L [1 ]
Delcan, JL [1 ]
机构
[1] UNIV COMPLUTENSE MADRID, HOSP GEN GREGORIO MARANON,DEPT CARDIOL, LAB ELECTROFISIOL,FAC MED, E-28007 MADRID, SPAIN
关键词
D O I
10.1016/0735-1097(95)00562-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives. This study sought to analyze two new criteria along with other known predictors of success of radiofrequency ablation. Background. Although the overall success rate of radiofrequency ablation of accessory pathways is high, the individual predictive value of each of the established criteria is low. Methods. We prospectively studied the local electrograms obtained before the application of radiofrequency energy in 33 patients with a left-sided concealed accessory pathway successfully ablated. Two new criteria (''pseudodisappearance'' during tachycardia of a bipolar atrial electrogram visible during sinus rhythm and the presence of an ''atrial notch'' in the ascending limb of the unipolar ventricular electrogram during tachycardia:) were studied along with other known predictors. Electrograms recorded at a total of 157 sites were analyzed (33 successful applications, 124 failures). Results. Electrogram characteristics that were predictive of success during ablation on the basis of univariate analyses were a pseudodisappearance criterion (p < 0.001), the presence of a Kent potential (p < 0.005) and the presence of an ''atrial notch'' (p < 0.005). After adjustment for between-patient differences, logistic regression analysis showed that only the ''pseudodisappearance'' criterion (odds ratio [OR] 7.2, 95% confidence interval [CI] 1.2 to 42.5, p < 0.03) and the presence of a Kent potential (OR 2.4, 95% CI 1.01 to 5.79, p < 0.05) had independent predictive value. Conclusions. The pseudodisappearance during tachycardia or ventricular pacing of a bipolar atrial electrogram present during sinus rhythm is associated with a good outcome during radiofrequency ablation of concealed accessory pathways. These observations may help to ablate accessory pathways and to avoid missing appropriate sites for ablation when the atrial activation is not clearly visible at the local electrogram.
引用
收藏
页码:853 / 859
页数:7
相关论文
共 18 条
[1]   ELECTROGRAM CRITERIA FOR IDENTIFICATION OF APPROPRIATE TARGET SITES FOR RADIOFREQUENCY CATHETER ABLATION OF ACCESSORY ATRIOVENTRICULAR CONNECTIONS [J].
CALKINS, H ;
KIM, YN ;
SCHMALTZ, S ;
SOUSA, J ;
ELATASSI, R ;
LEON, A ;
KADISH, A ;
LANGBERG, JJ ;
MORADY, F .
CIRCULATION, 1992, 85 (02) :565-573
[2]   RADIOFREQUENCY CATHETER ABLATION OF ACCESSORY ATRIOVENTRICULAR CONNECTIONS IN 250 PATIENTS - ABBREVIATED THERAPEUTIC APPROACH TO WOLFF-PARKINSON-WHITE SYNDROME [J].
CALKINS, H ;
LANGBERG, J ;
SOUSA, J ;
ELATASSI, R ;
LEON, A ;
KOU, W ;
KALBFLEISCH, S ;
MORADY, F .
CIRCULATION, 1992, 85 (04) :1337-1346
[3]   HISTOPATHOLOGY OF MONOPOLAR TRANSCATHETER RADIOFREQUENCY ABLATION AT THE MITRAL-VALVE ANNULUS [J].
CHIN, MC ;
SCHUENEMEYER, T ;
FINKEBEINER, WE ;
STERN, RA ;
SCHEINMAN, MM ;
LANGBERG, JJ .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1991, 14 (11) :1956-1960
[4]  
FARRE J, 1987, CARDIAC ARRHYTHMIAS, P243
[5]  
GURSOY S, 1992, HERZ, V17, P151
[6]   ELECTROGRAM PATTERNS PREDICTIVE OF SUCCESSFUL CATHETER ABLATION OF ACCESSORY PATHWAYS - VALUE OF UNIPOLAR RECORDING MODE [J].
HAISSAGUERRE, M ;
DARTIGUES, JF ;
WARIN, JF ;
LEMETAYER, P ;
MONTSERRAT, P ;
SALAMON, R .
CIRCULATION, 1991, 84 (01) :188-202
[7]   LOCALIZATION OF LEFT FREE-WALL AND POSTEROSEPTAL ACCESSORY ATRIOVENTRICULAR PATHWAYS BY DIRECT RECORDING OF ACCESSORY PATHWAY ACTIVATION [J].
JACKMAN, WM ;
FRIDAY, KJ ;
FITZGERALD, DM ;
BOWMAN, AJ ;
YEUNGLAIWAI, JA ;
LAZZARA, R .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1989, 12 (01) :204-214
[8]   CATHETER ABLATION OF ACCESSORY ATRIOVENTRICULAR PATHWAYS (WOLFF-PARKINSON-WHITE SYNDROME) BY RADIOFREQUENCY CURRENT [J].
JACKMAN, WM ;
WANG, XZ ;
FRIDAY, KJ ;
ROMAN, CA ;
MOULTON, KP ;
BECKMAN, KJ ;
MCCLELLAND, JH ;
TWIDALE, N ;
HAZLITT, HA ;
PRIOR, MI ;
MARGOLIS, PD ;
CALAME, JD ;
OVERHOLT, ED ;
LAZZARA, R .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (23) :1605-1611
[9]   RADIOFREQUENCY CATHETER ABLATION OF ACCESSORY PATHWAYS - A LEARNING-EXPERIENCE [J].
LEATHER, RA ;
LEITCH, JW ;
KLEIN, GJ ;
GUIRAUDON, GM ;
YEE, R ;
KIM, YH .
AMERICAN JOURNAL OF CARDIOLOGY, 1991, 68 (17) :1651-1655
[10]   CURATIVE PERCUTANEOUS CATHETER ABLATION USING RADIOFREQUENCY ENERGY FOR ACCESSORY PATHWAYS IN ALL LOCATIONS - RESULTS IN 100 CONSECUTIVE PATIENTS [J].
LESH, MD ;
VANHARE, GF ;
SCHAMP, DJ ;
CHIEN, W ;
LEE, MA ;
GRIFFIN, JC ;
LANGBERG, JJ ;
COHEN, TJ ;
LURIE, KG ;
SCHEINMAN, MM .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1992, 19 (06) :1303-1309