Clinical Use of Misoprostol in Nonpregnant Women: Review Article

被引：23

作者：

Choksuchat, Chainarong ^{[1
]}

机构：

[1] Prince Songkla Univ, Fac Med, Dept Obstet & Gynecol, Hat Yai 90110, Songkhla, Thailand

来源：

JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY | 2010年 / 17卷 / 04期

关键词：

Biopsy; Endometrium; Gynecology; Hysteroscopy; Intrauterine device; Intrauterine insemination; IUD; IUI; Misoprostol; Myomectomy; RANDOMIZED CONTROLLED-TRIAL; PLACEBO-CONTROLLED TRIAL; GONADOTROPIN-RELEASING-HORMONE; CERVICAL PRIMING PRIOR; VAGINAL MISOPROSTOL; OPERATIVE HYSTEROSCOPY; DOUBLE-BLIND; POSTMENOPAUSAL WOMEN; ORAL MISOPROSTOL; NITRIC-OXIDE;

D O I：

10.1016/j.jmig.2010.03.015

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Misoprostol, a prostaglandin E-1 derivative, has been widely used in nonpregnant women because of its cervical ripening and uterotonic effects. A large number of studies have demonstrated its effectiveness in enhancing ease of cervical dilation. This review article describes its pharmacokinetic profile and the relationship between prostaglandins and cervical ripening and uterine contraction and provides a review of the clinical use of misoprostol in nonpregnant women including cervical priming before hysteroscopy, before insertion of an intrauterine device, in endometrium biopsy, preoperatively in myomectomy, and before intrauterine insemination to improve pregnancy rates. Adverse effects are also described. Journal of Minimally Invasive Gynecology (2010) 17,449-455 (c) 2010 AAGL. All rights reserved.

引用

页码：449 / 455

页数：7

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