Glycine transport inhibitors and the treatment of schizophrenia

被引:76
作者
Javitt, Daniel C. [1 ]
机构
[1] Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA
关键词
D O I
10.1016/j.biopsych.2007.09.017
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:6 / 8
页数:3
相关论文
共 10 条
[1]   The Cognitive and Negative Symptoms in Schizophrenia, Trial (CONSIST): The efficacy of glutamatergic agents for negative symptoms and cognitive impairments [J].
Buchanan, Robert W. ;
Javitt, Daniel C. ;
Marder, Stephen R. ;
Schooler, Nina R. ;
Gold, James M. ;
McMahon, Robert P. ;
Heresco-Levy, Uriel ;
Carpenter, William T. .
AMERICAN JOURNAL OF PSYCHIATRY, 2007, 164 (10) :1593-1602
[2]  
JAVITT D C, 1987, Hillside Journal of Clinical Psychiatry, V9, P12
[3]   Glutamate and schizophrenia:: Phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions [J].
Javitt, Daniel C. .
INTEGRATING THE NEUROBIOLOGY OF SCHIZOPHRENIA, 2007, 78 :69-+
[4]   Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients [J].
Javitt, DC .
CURRENT OPINION IN PSYCHIATRY, 2006, 19 (02) :151-157
[5]  
JAVITT DC, 1991, AM J PSYCHIAT, V148, P1301
[6]   Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine - Implications for glutamatergic and dopaminergic model psychoses and cognitive function [J].
Krystal, JH ;
Perry, EB ;
Gueorguieva, R ;
Belger, A ;
Madonich, SH ;
Abi-Dargham, A ;
Cooper, TB ;
MacDougall, L ;
Abi-Saab, W ;
D'Souza, DC .
ARCHIVES OF GENERAL PSYCHIATRY, 2005, 62 (09) :985-995
[7]   Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia - A randomized, double-blind, placebo-controlled study [J].
Lane, HY ;
Chang, YC ;
Liu, YC ;
Chiu, CC ;
Tsai, GE .
ARCHIVES OF GENERAL PSYCHIATRY, 2005, 62 (11) :1196-1204
[8]   Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial [J].
Patil, Sandeep T. ;
Zhang, Lu ;
Martenyi, Ferenc ;
Lowe, Stephen L. ;
Jackson, Kimberley A. ;
Andreev, Boris V. ;
Avedisova, Alla S. ;
Bardenstein, Leonid M. ;
Gurovich, Issak Y. ;
Morozova, Margarita A. ;
Mosolov, Sergey N. ;
Neznanov, Nikolai G. ;
Reznik, Alexander M. ;
Smulevich, Anatoly B. ;
Tochilov, Vladimir A. ;
Johnson, Bryan G. ;
Monn, James A. ;
Schoepp, Darryle D. .
NATURE MEDICINE, 2007, 13 (09) :1102-1107
[9]   Glycine transporter 1 inhibitors and modulation of NMDA receptor-mediated excitatory neurotransmission [J].
Sur, Cyrille ;
Kinney, Gene G. .
CURRENT DRUG TARGETS, 2007, 8 (05) :643-649
[10]   Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a procognitive and antipsychotic phenotypic profile [J].
Yee, BK ;
Balic, E ;
Singer, P ;
Schwerdel, C ;
Grampp, T ;
Gabernet, L ;
Knuesel, I ;
Benke, D ;
Feldon, J ;
Mohler, H ;
Boison, D .
JOURNAL OF NEUROSCIENCE, 2006, 26 (12) :3169-3181