Hyperthyroidism secondary to a hydatidiform mole

被引：1

作者：

Grzechocinska, Barbara ^{[1
]}

Gajewska, Malgorzata ^{[1
]}

Kedzierski, Maciej ^{[1
]}

Gajda, Sylwia ^{[2
]}

Jedrzejak, Piotr ^{[1
]}

Wielgos, Miroslaw ^{[1
]}

机构：

[1] Med Univ Warsaw, Dept Obstet & Gynecol 1, Warsaw, Poland

[2] M Sklodowska Curie Mem Inst, Ctr Canc, Endocrine Oncol & Nucl Med Clin, Warsaw, Poland

来源：

GINEKOLOGIA POLSKA | 2021年 / 92卷 / 10期

关键词：

gestational trophoblastic disease; hydatidiform mole; hCG; hyperthyroidism;

D O I：

10.5603/GP.a2021.0185

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The case presented in the article is that of a 47-year-old female patient with hyperthyroidism induced by a hydatidiform mole. Attention was drawn to the necessity of preparing the patient for a procedure with drugs that stabilize the hormonal activity of the thyroid. The removal of the hydatidiform mole resulted in gradual normalization of thyroid hormone levels. The trophoblast has a hormonal activity, secrete hCG (human chorionic gonadotropin). The hCG partial structural homology causes affinity to the TSH (thyroid stimulating hormone) receptor. The higher the weight of the trophoblast, the higher the production and concentration of hCG in the blood. Therefore, gestational trophoblastic disease may be accompanied by hyperthyroidism. The problem is frequently described, however, due to the risk of developing thyroid storm, it cannot be overlooked [1].

引用

页码：741 / 742

页数：2

共 4 条

[1] THYROID STORM-INDUCED MULTI-ORGAN FAILURE IN THE SETTING OF GESTATIONAL TROPHOBLASTIC DISEASE [J].