Degradation of fullerene C60 by human myeloperoxidase and some reaction products

被引:3
作者
Piotrovskiy, Levon Borisovich [1 ]
Litasova, Elena Viktorovna [1 ]
Sokolov, Alexey Victorovich [1 ]
Iljin, Victor Vladimirovich [1 ]
Utsal, Viktor Arnoldovich [2 ]
Zhurkovich, Inna Konstantinovna [2 ]
机构
[1] Inst Expt Med, Acad Pavlov Str 12, St Petersburg 197376, Russia
[2] Inst Toxicol Fed Biomed Agcy, St Petersburg, Russia
关键词
Fullerene C-60; nanoC(60); biodegradation; myeloperoxidase; hypochlorite; CARBON NANOTUBES; HYPOCHLOROUS ACID; BIODEGRADATION; OXIDATION; WATER; TRANSFORMATION; NANOPARTICLES; MECHANISMS; RADICALS; IMPACT;
D O I
10.1080/1536383X.2019.1686620
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The biodegradation of the fullerene molecule C-60 under the action of the human myeloperoxidase enzyme accompanied by a complete loss of the topology of the fullerene core. Analysis of this reaction mixture using UV and FTIR spectroscopy, chromatographic and mass spectrometry methods showed that the degradation proceeds without the formation of significant amounts of hydroxylated compounds. Among other intermediate compounds aromatic compounds were detected.
引用
收藏
页码:196 / 201
页数:6
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