Eco-friendly approach to access of quinoxaline derivatives using nanostructured pyrophosphate Na2PdP2O7 as a new, efficient and reusable heterogeneous catalyst

被引：20

作者：

Danoun, Karim ^{[1
,2
]}

Essamlali, Younes ^{[1
]}

Amadine, Othmane ^{[1
]}

Mahi, Hassan ^{[1
]}

Zahouily, Mohamed ^{[1
,2
]}

机构：

[1] Moroccan Fdn Adv Sci Innovat & Res MAScIR, VARENA Ctr, Rue Mohamed El Jazouli, Rabat 10100, Morocco

[2] Univ Hassan II Casablanca, Lab Mat Catalysis & Valorizat Nat Resources URAC, FST Mohammedia, BP 146, Casablanca 20650, Morocco

来源：

BMC CHEMISTRY | 2020年 / 14卷 / 01期

关键词：

Nanostructured pyrophosphate; Heterogeneous catalysis; Recyclable catalyst; Quinoxalines; 1,2-Diamine; 1,2-Dicarbonyl; CONDENSATION; 1,2-DIAMINES; OXIDATION; PROTOCOL; ACID;

D O I：

10.1186/s13065-020-0662-z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the present study, we report the synthesis of various quinoxaline derivatives from direct condensation of substituted aromatic 1,2-diamine with 1,2-dicarbonyl catalyzed by nanostructured pyrophosphate Na2PdP2O7 as a new highly efficient bifunctionalheterogeneous catalyst. The quinoxaline synthesis was performed in ethanol as a green and suitable solvent at ambient temperature to afford the desired quinoxalines with good to excellent yields in shorter reaction times. Many Quinoxaline derivatives were successfully synthesized using various 1,2-diketones and 1,2-diamines at room temperature. Catalyst reusability showed that the Na2PdP2O7 catalyst exhibited excellent recyclability without significant loss in its catalytic activity after five consecutive cycles.

引用

页数：13

共 45 条

[1] Direct and catalytic synthesis of quinoxaline derivatives from epoxides and ene-1,2-diamines [J].