A coumarin derivative covalently immobilized on sensing membrane as a fluorescent carrier for nitrofurazone

被引：32

作者：

Jiao, CX

Niu, CG

Chen, LX

Shen, GL

Yu, RQ ^{[1
]}

机构：

[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Peoples R China

[2] Hunan Univ, Dept Environm Sci & Engn, Changsha 410082, Peoples R China

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2003年 / 376卷 / 03期

基金：

中国国家自然科学基金;

关键词：

optical sensor; coumarin derivative; fluorescence quenching; covalent immobilization; nitrofurazone;

D O I：

10.1007/s00216-003-1909-y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A coumarin derivative 4-methyl-8-methylacrylamide-2H, 5H-pyrano [3, 2-C] benzpyran 2, 5-dione (MMPBD) has been synthesized as a fluorescent carrier for preparing an optical chemical sensor. The carrier is immobilized on a quartz glass plate surface treated with a silanizing agent to prevent the leakage of the dye. This MMPBD sensor can be utilized for a nitrofurazone (NF) assay based on fluorescence quenching. The sensor shows good repeatability, a long lifetime and a fast response of less then 50 s. NF can be determined in the range between 1.0x10(-6)-1.0x10(-3) mol L-1 with a detection limit Of 8.0x10(-7) mol L-1 at pH 7.0.

引用

页码：392 / 398

页数：7

共 21 条

[1] Optical oxygen detection based an luminescence change of metalloporphyrins immobilized in poly(isobutylmethacrylate-co-trifluoroethylmethacrylate) film [J].

Amao, Y ;

Miyashita, T ;

Okura, I .

ANALYTICA CHIMICA ACTA, 2000, 421 (02) :167-174

[2]

CHENG TS, 1990, J E CHINA I CHEM TEC, V16, P176

[3] A DOUBLE-PRISM BEAM EXPANDER FOR PULSED DYE-LASERS [J].

DUARTE, FJ ;

PIPER, JA .

OPTICS COMMUNICATIONS, 1980, 35 (01) :100-104

[4] ELECTRON-TRANSFER MECHANISM OF FLUORESCENCE QUENCHING IN POLAR SOLVENTS .1. DICYANOBENZENE AS QUENCHER [J].

GRELLMANN, KH ;

WELLER, A ;

WATKINS, AR .

JOURNAL OF PHYSICAL CHEMISTRY, 1972, 76 (04) :469-+

[5] Molecular design, characterization, and application of multiinformation dyes for multidimensional optical chemical sensings. 2. Preparation of the optical sensing membranes for the simultaneous measurements of pH and water content in organic media [J].

Hisamoto, H ;

Manabe, Y ;

Yanai, H ;

Tohma, H ;

Yamada, T ;

Suzuki, K .

ANALYTICAL CHEMISTRY, 1998, 70 (07) :1255-1261

[6] SYNTHESES OF FLUORESCENT DYES .9. NEW 4-HYDROXYCOUMARINS, 4-HYDROXY-2-QUINOLONES, 2H,5H-PYRANO[3,2-C]BENZOPYRAN-2,5-DIONES AND 2H,5H-PYRANO[3,2-C]QUINOLINE-2,5-DIONES [J].

KNIERZINGER, A ;

WOLFBEIS, OS .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1980, 17 (02) :225-229

[7]

KWEN JW, 1989, SAE MULLI, V29, P719

[8]

Lakowicz J. R., 2010, PRINCIPLES FLUORESCE

[9] Optical sensor for oxygen using a porphyrin-doped sol-gel glass [J].

Lee, SK ;

Okura, I .

ANALYST, 1997, 122 (01) :81-84

[10]

LI ZW, 1996, ACTA MED SINICA, V9, P300

← 1 2 3 →