Magnetic Nanoparticles as Contrast Agents for Magnetic Resonance Imaging

被引：24
作者：
Chaughule, R. S. [1 ]
Purushotham, S. [2 ]
Ramanujan, R. V. [3 ]
机构：
[1] Ramnarain Ruia Coll, Bombay 400019, Maharashtra, India
[2] Nanyang Technol Univ, Energy Res Inst, Singapore 637553, Singapore
[3] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES | 2012年 / 82卷 / 03期
关键词：
Magnetic nanoparticles; SPIONs; MRI; MRI contrast agents; IRON-OXIDE NANOPARTICLES; PROSTATE-CANCER; GOLD NANOPARTICLES; PHASE-I; NANOCRYSTALS; THERMOTHERAPY; PARTICLES; UNIFORM; MRI; PHARMACOKINETICS;
D O I：
10.1007/s40010-012-0038-4
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In the field of nanotechnology, new magnetic materials such as superparamagnetic iron oxide nanoparticles (NPs) have been developed as novel magnetic resonance imaging (MRI) contrast agents. This is due to their unique properties such as large surface area, biodegradability and superparamagnetic properties. This review article discusses the development of such contrast agents. The effect of relaxation times of magnetic NPs (MNPs) with varying size, surface modification etc. on the development of contrast in MRI is also discussed. Such MNPs are now commercially available because of their safety and high sensitivity.
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页码：257 / 268
页数：12
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