Extraction of gatifloxacin in water by use of ionic liquid-salt aqueous two-phase system

An ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate( [BMIM] BF4) / salt aqueous two-phase systems (ATPS) was presented as a simple, rapid and effective sample pretreatment technique coupled with double-beam UV-Vis spectrophotometer for analysis of gatifloxacin in water. For the purpose to choose optimal conditions, various factors were considered systematically, and the results indicated that the pH value, the salt-out ability of salt and the amount of [BMIM] BF4 had great influence on phase separation and extraction. Under the optimal condition, gatifloxacin in different concentration were enriched and determined, the recovery was 87.3-91.5%.