EVALUATION OF RECTAL DOSE DURING HIGH-DOSE-RATE INTRACAVITARY BRACHYTHERAPY FOR CERVICAL CARCINOMA

被引:4
作者
Sha, Rajib Lochan
Reddy, Palreddy Yadagiri
Rao, Ramakrishna
Muralidhar, Kanaparthy R.
Kudchadker, Rajat J. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Radiat Phys, Unit 2102, Houston, TX 77030 USA
关键词
Uterine cervical carcinoma; High-dose-rate intracavitary brachytherapy; Rectal dose; RADIATION-THERAPY; UTERINE CERVIX; IMPLANTS; BLADDER;
D O I
10.1016/j.meddos.2010.09.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
High-dose-rate intracavitary brachytherapy (HDR-ICBT) for carcinoma of the uterine cervix often results in high doses being delivered to surrounding organs at risk (OARs) such as the rectum and bladder. Therefore, it is important to accurately determine and closely monitor the dose delivered to these OARs. In this study, we measured the dose delivered to the rectum by intracavitary applications and compared this measured dose to the International Commission on Radiation Units and Measurements rectal reference point dose calculated by the treatment planning system (TPS). To measure the dose, we inserted a miniature (0.1 cm(3)) ionization chamber into the rectum of 86 patients undergoing radiation therapy for cervical carcinoma. The response of the miniature chamber modified by 3 thin lead marker rings for identification purposes during imaging was also characterized. The difference between the TPS-calculated maximum dose and the measured dose was <5% in 52 patients, 5-10% in 26 patients, and 10-14% in 8 patients. The TPS-calculated maximum dose was typically higher than the measured dose. Our study indicates that it is possible to measure the rectal dose for cervical carcinoma patients undergoing HDR-ICBT. We also conclude that the dose delivered to the rectum can be reasonably predicted by the TPS-calculated dose. (C) 2011 American Association of Medical Dosimetrists.
引用
收藏
页码:377 / 382
页数:6
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