R05-1415 (Reg. No. GP-377, PI 659697) and R05-1772 (Reg. No. GP-378, PI 659698) soybean [Glycine max (L.) Merr.] lines were developed by the Arkansas Agricultural Experiment Station, Fayetteville, AR and were released as high-protein lines with a moderately high yield potential. R05-1415 is an F(3) plant selection from the cross between 'MFS-591' and V96-4486, whereas R05-1772 is an F(4) plant selection from the cross between R95-1705 and V96-4181. Both R05-1415 and R05-1772 are mid-maturity-group-V lines. The yield potential of R05-1415 and R05-1772 was 94 and 91% that of the check '5002T' across multiple environments. The average protein content of R05-1415 and R05-1772 was 469 and 461 g kg(-1), which was 17 and 15% greater than that of 5002T, respectively.