Shifts in the Proportion of Distant Stage Early-Onset Colorectal Adenocarcinoma in the United States

被引:17
作者
Montminy, Eric M. [1 ]
Zhou, Meijiao [2 ]
Maniscalco, Lauren [2 ]
Heda, Rajiv [3 ]
Kim, Michelle Kang [4 ]
Patel, Swati G. [5 ,6 ]
Wu, Xiao-Cheng [2 ]
Itzkowitz, Steven H. [4 ]
Karlitz, Jordan J. [5 ,7 ]
机构
[1] Tulane Univ, Sch Med, Div Gastroenterol, 1430 Tulane Ave, New Orleans, LA 70112 USA
[2] Louisiana State Univ, Hlth Sci Ctr, Louisiana Tumor Registry, Dept Epidemiol, New Orleans, LA USA
[3] Tulane Univ, Sch Med, Dept Internal Med, 1430 Tulane Ave, New Orleans, LA 70112 USA
[4] Icahn Sch Med Mt Sinai, Div Gastroenterol, New York, NY 10029 USA
[5] Univ Colorado, Sch Med, Div Gastroenterol, Aurora, CO USA
[6] Rocky Mt Reg Vet Affairs Med Ctr, Aurora, CO USA
[7] Denver Hlth Med Ctr, Div Gastroenterol, Denver, CO 80204 USA
关键词
CANCER;
D O I
10.1158/1055-9965.EPI-21-0611
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Carcinoids, frequently classified as "colorectal incidence rates (IR) and have distinct staging distributions compared to often advanced stage adenocarcinomas (screening target). Thus, assessing temporal shifts in early-onset distant stage adenocarcinoma can impact public health. Methods: 2000-2016 Surveillance Epidemiology and End Results (SEER) 18 yearly adenocarcinoma IRs were stratified by stage (in situ, localized, regional, distant), age (20-29, 30-39, 40-49, 50-54-yearolds), subsite (colorectal, rectal-only, colon-only), and race [nonpatients. Three-year average annual IR changes (pooled 2000-2002 IRs compared with 2014-2016) and cancer stage proportions (percent contribution of each cancer stage) were calculated. Results: Comparing 2000-2002 with 2014-2016, the steepest percent increases are in distant stage cancers. Colon-only, distant adenocarcinoma increased most in 30-39-year-olds (49%, 0.75/ 100,000-*1.12/100,00, P < 0.05). Rectal-only, distant stage increases
引用
收藏
页码:334 / 341
页数:8
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