Persistence of SARS-CoV-2 RNA in post-mortem swab 35 days after death: A case report

被引:20
作者
Beltempo, Pasquale [1 ]
Curti, Serena Maria [1 ]
Maserati, Renato [2 ]
Gherardi, Mirella [1 ]
Castelli, Maurizio [1 ]
机构
[1] Azienda USL Valle Aosta, SC Med Legale, Local Amer 7-L, I-11020 Quart, AO, Italy
[2] Fdn IRCCS Policlin San Matteo, Dipartimento Sci Med & Malattie Infett, Piazzale Golgi 19, I-27100 Pavia, PV, Italy
关键词
SARS-CoV-2; COVID-19; Post-mortem swab; Post-mortem diagnosis; Biosafety; Autopsy;
D O I
10.1016/j.forsciint.2020.110653
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Post-mortem swabs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA detection have been recommended by several Scientific Committees and Institutions as a standard procedure for post-mortem assessment of potential Coronavirus Disease-19 (COVID-19) related deaths. To date there is no data about the SARS-CoV-2 RNA detectability period in human bodies after death. The present case documents the persistence of SARS-CoV-2 RNA in the upper respiratory tract 35-days after death. Postmortem swabs could be used as a valuable tool in preventive evaluation of the risks-benefits ratio associated with autopsy execution. SARS-CoV-2 RNA post-mortem detection could have a key diagnostic role in deaths lacking medical assistance, unattended deaths, and patients with multiple comorbidities. Based on the present report, staged post-mortem swabs should be performed even after a long postmortem interval. (C) 2020 Elsevier B.V. All rights reserved.
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页数:3
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