Do Not Assume Symptoms Indicate Failure of Anti-Tumor Necrosis Factor Therapy in Crohn's Disease

被引：20

作者：

Bruining, David H. ^{[2
]}

Sandborn, William J. ^{[1
]}

机构：

[1] Univ Calif San Diego, Div Gastroenterol, La Jolla, CA 92093 USA

[2] Mayo Clin, Div Gastroenterol & Hepatol, Coll Med, Rochester, MN USA

来源：

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | 2011年 / 9卷 / 05期

关键词：

Anti-TNF Therapy; Crohn's Disease; Treatment Failure; INFLAMMATORY-BOWEL-DISEASE; SCHEDULED MAINTENANCE TREATMENT; ADALIMUMAB TREATMENT; CERTOLIZUMAB PEGOL; EPISODIC TREATMENT; RANDOMIZED-TRIAL; CT ENTEROGRAPHY; RISK-FACTORS; INFLIXIMAB; EFFICACY;

D O I：

10.1016/j.cgh.2011.01.019

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

It is a challenge to monitor patients with Crohn's disease who remain symptomatic despite anti-tumor necrosis factor therapy. Clinicians must use a systematic approach for each patient and obtain objective evidence about disease activity and response to therapy. Alternate etiologies for symptoms should be sought and treated, if found. Active Crohn's disease despite therapy requires reassessment and adjustments to management plans.

引用

页码：395 / 399

页数：5

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