Role of Tyramine Synthesis by Food-Borne Enterococcus durans in Adaptation to the Gastrointestinal Tract Environment

被引:46
作者
Fernandez de Palencia, Pilar [1 ]
Fernandez, Maria [2 ]
Luz Mohedano, Maria [1 ]
Ladero, Victor [2 ]
Quevedo, Cristina [1 ]
Alvarez, Miguel A. [2 ]
Lopez, Paloma [1 ]
机构
[1] CSIC, Ctr Invest Biol, Madrid 28040, Spain
[2] CSIC, Inst Prod Lacteos Asturias, Villaviciosa 33300, Asturias, Spain
关键词
BIOGENIC-AMINES;
D O I
10.1128/AEM.01411-10
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Biogenic amines in food constitute a human health risk. Here we report that tyramine-producing Enterococcus durans strain IPLA655 (from cheese) was able to produce tyramine under conditions simulating transit through the gastrointestinal tract. Activation of the tyramine biosynthetic pathway contributed to binding and immunomodulation of enterocytes.
引用
收藏
页码:699 / 702
页数:4
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