Planning experiments: Updated guidance on experimental design and analysis and their reporting III

被引：463

作者：

Curtis, Michael J. ^{[1
]}

Alexander, Stephen P. H. ^{[2
]}

Cirino, Giuseppe ^{[3
]}

George, Christopher H. ^{[4
]}

Kendall, David A. ^{[2
]}

Insel, Paul A. ^{[5
]}

Izzo, Angelo A. ^{[3
]}

Ji, Yong ^{[6
]}

Panettieri, Reynold A. ^{[7
]}

Patel, Hemal H. ^{[5
]}

Sobey, Christopher G. ^{[8
]}

Stanford, S. Clare ^{[9
]}

Stanley, Phil ^{[10
]}

Stefanska, Barbara ^{[11
]}

Stephens, Gary J. ^{[12
]}

Teixeira, Mauro M. ^{[13
]}

Vergnolle, Nathalie ^{[14
]}

Ahluwalia, Amrita ^{[15
]}

机构：

[1] Kings Coll London, London, England

[2] Univ Nottingham, Nottingham, England

[3] Univ Naples Federico II, Naples, Italy

[4] Swansea Univ, Swansea, W Glam, Wales

[5] Univ Calif San Diego, San Diego, CA 92182 USA

[6] Nanjing Med Univ, Nanjing, Peoples R China

[7] Rutgers State Univ, Newark, NJ 07103 USA

[8] La Trobe Univ, Bundoora, Vic, Australia

[9] UCL, London, England

[10] UCB Pharma, Slough, Berks, England

[11] Univ British Columbia, Vancouver, BC, Canada

[12] Univ Reading, Reading, Berks, England

[13] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil

[14] INSERM, Toulouse, France

[15] Queen Mary Univ London, William Harvey Res Inst, London, England

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 2022年 / 179卷 / 15期

关键词：

D O I：

10.1111/bph.15868

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Scientists who plan to publish in British Journal of Pharmacology (BJP) must read this article before undertaking a study. This editorial provides guidance for the design of experiments. We have published previously two guidance documents on experimental design and analysis (Curtis et al., 2015; Curtis et al., 2018). This update clarifies and simplifies the requirements on design and analysis for BJP manuscripts. This editorial also details updated requirements following an audit and discussion on best practice by the BJP editorial board. Explanations for the requirements are provided in the previous articles. Here, we address new issues that have arisen in the course of handling manuscripts and emphasise three aspects of design that continue to present the greatest challenge to authors: randomisation, blinded analysis and balance of group sizes.

引用

页码：3907 / 3913

页数：7

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