The C(sp3)-H bond functionalization of thioethers with styrenes with insight into the mechanism

被引：9

作者：

Yan, Zhan ^{[1
,2
]}

Wang, Nai-Xing ^{[1
]}

Zhang, Lei-Yang ^{[1
]}

Wu, Yue-Hua ^{[1
]}

Li, Jian-Li ^{[2
]}

She, Meng-Yao ^{[2
]}

Gao, Xue-Wang ^{[1
]}

Feng, Ke ^{[1
]}

Xing, Yalan ^{[3
]}

机构：

[1] Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China

[2] Northwest Univ, Coll Chem & Mat Sci, Xian 710127, Peoples R China

[3] William Paterson Univ New Jersey, Dept Chem, Wayne, NJ 07470 USA

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2022年 / 20卷 / 29期

关键词：

ETHERS; ALKENES; DIFUNCTIONALIZATION; VINYLARENES; ALKYLATION;

D O I：

10.1039/d2ob00872f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A metal-free inactive C(sp(3))-H bond functionalization of thioethers with styrenes using TBHP as an initiator and DBU as a base has been developed. This transformation has broken through the low activity of thioethers and realized moderate yields. Herein extended experiments were conducted to confirm the radical relay process, reaction energy and intermediate transformations.

引用

页码：5845 / 5851

页数：7

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