The C(sp3)-H bond functionalization of thioethers with styrenes with insight into the mechanism

被引:9
作者
Yan, Zhan [1 ,2 ]
Wang, Nai-Xing [1 ]
Zhang, Lei-Yang [1 ]
Wu, Yue-Hua [1 ]
Li, Jian-Li [2 ]
She, Meng-Yao [2 ]
Gao, Xue-Wang [1 ]
Feng, Ke [1 ]
Xing, Yalan [3 ]
机构
[1] Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China
[2] Northwest Univ, Coll Chem & Mat Sci, Xian 710127, Peoples R China
[3] William Paterson Univ New Jersey, Dept Chem, Wayne, NJ 07470 USA
关键词
ETHERS; ALKENES; DIFUNCTIONALIZATION; VINYLARENES; ALKYLATION;
D O I
10.1039/d2ob00872f
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A metal-free inactive C(sp(3))-H bond functionalization of thioethers with styrenes using TBHP as an initiator and DBU as a base has been developed. This transformation has broken through the low activity of thioethers and realized moderate yields. Herein extended experiments were conducted to confirm the radical relay process, reaction energy and intermediate transformations.
引用
收藏
页码:5845 / 5851
页数:7
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