Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis

被引:78
作者
Fajar, Jonny Karunia [1 ]
Sallam, Malik [2 ,3 ,4 ]
Soegiarto, Gatot [5 ]
Sugiri, Yani Jane [6 ]
Anshory, Muhammad [1 ,7 ]
Wulandari, Laksmi [8 ]
Kosasih, Stephanie Astrid Puspitasari [9 ]
Ilmawan, Muhammad [10 ]
Kusnaeni, Kusnaeni [11 ]
Fikri, Muhammad [11 ]
Putri, Frilianty [12 ]
Hamdi, Baitul [13 ]
Pranatasari, Izza Dinalhaque [14 ]
Aina, Lily [15 ]
Maghfiroh, Lailatul [16 ]
Ikhriandanti, Fernanda Septi [17 ]
Endiaverni, Wa Ode [18 ]
Nugraha, Krisna Wahyu [18 ]
Wiranudirja, Ory [18 ]
Edinov, Sally [19 ]
Hamdani, Ujang [18 ]
Rosyidah, Lathifatul [18 ]
Lubaba, Hanny [18 ]
Ariwibowo, Rinto [18 ]
Andistyani, Riska [18 ]
Fitriani, Ria [20 ]
Hasanah, Miftahul [21 ]
Nafis, Fardha Ad Durrun [21 ]
Tamara, Fredo [1 ]
Latamu, Fitri Olga [1 ]
Kusuma, Hendrix Indra [22 ,23 ,24 ]
Rabaan, Ali A. [25 ,26 ,27 ]
Alhumaid, Saad [28 ]
Al Mutair, Abbas [29 ,30 ,31 ,32 ]
Garout, Mohammed [33 ]
Halwani, Muhammad A. [34 ]
Alfaresi, Mubarak [35 ,36 ]
Al Azmi, Reyouf [37 ]
Alasiri, Nada A. [38 ]
Alshukairi, Abeer N. [26 ,39 ]
Dhama, Kuldeep [40 ]
Harapan, Harapan [22 ,41 ,42 ]
机构
[1] Univ Brawijaya, Fac Med, Dept Internal Med, Brawijaya Internal Med Res Ctr, Malang 65145, Indonesia
[2] Univ Jordan, Dept Pathol Microbiol & Forens Med, Sch Med, Amman 11942, Jordan
[3] Jordan Univ Hosp, Dept Clin Labs & Forens Med, Amman 11942, Jordan
[4] Lund Univ, Fac Med, Dept Translat Med, S-22184 Malmo, Sweden
[5] Univ Airlangga, Fac Med, Dept Internal Med, Div Allergy & Immunol, Surabaya 60286, Indonesia
[6] Univ Brawijaya, Fac Med, Dept Pulmonol & Resp Med, Malang 65145, Indonesia
[7] Univ Brawijaya, Fac Med, Dept Internal Med, Div Allergy & Immunol, Malang 65145, Indonesia
[8] Univ Airlangga, Fac Med, Dept Pulmonol & Resp Med, Surabaya 60286, Indonesia
[9] Univ Brawijaya, Fac Med, Malang 65145, Indonesia
[10] Univ Brawijaya, Fac Med, Dept Urol, Malang 65145, Indonesia
[11] Inst Pertanian Bogor, Fac Matemat & Sci, Bogor 16680, Indonesia
[12] Inst Pertanian Bogor, Sch Vet Med & Biomed, Bogor 16680, Indonesia
[13] Univ Airlangga, Fac Econ & Business, Surabaya 60286, Indonesia
[14] Univ Airlangga, Fac Publ Hlth, Surabaya 60286, Indonesia
[15] Univ Airlangga, Fac Pharm, Surabaya 60286, Indonesia
[16] Univ Airlangga, Fac Vet Med, Surabaya 60286, Indonesia
[17] Univ Airlangga, Fac Med, Surabaya 60286, Indonesia
[18] Univ Brawijaya, Fac Econ & Business, Malang 65145, Indonesia
[19] Riau Univ, Fac Econ & Business, Pekanbaru 28293, Indonesia
[20] Univ Brawijaya, Fac Adm Sci, Malang 65145, Indonesia
[21] Univ Brawijaya, Fac Anim Sci, Malang 65145, Indonesia
[22] Univ Syiah Kuala, Sch Med, Med Res Unit, Banda Aceh 23111, Indonesia
[23] Univ Syiah Kuala, Fac Math & Nat Sci, Darussalam 23111, Banda Aceh, Indonesia
[24] Univ Islam Negeri Ar Raniry, Fac Tarbiyah & Teacher Training, Banda Aceh 23111, Indonesia
[25] Johns Hopkins Aramco Healthcare, Mol Diagnost Lab, Dhahran 31311, Saudi Arabia
[26] Alfaisal Univ, Coll Med, Riyadh 11533, Saudi Arabia
[27] Univ Haripur, Dept Publ Hlth & Nutr, Haripur 22610, Pakistan
[28] Minist Hlth, Al Ahsa Hlth Cluster, Adm Pharmaceut Care, Al Hasa 31982, Saudi Arabia
[29] Almoosa Specialist Hosp, Res Ctr, Al Mubarrazs 36342, Saudi Arabia
[30] Princess Norah Bint Abdulrahman Univ, Coll Nursing, Riyadh 11564, Saudi Arabia
[31] Wollongong Univ, Sch Nursing, Wollongong, NSW 2522, Australia
[32] Prince Sultan Mil Coll Hlth Sci, Dept Nursing, Dhahran 33048, Saudi Arabia
[33] Umm Al Qura Univ, Fac Med, Dept Community Med & Hlth Care Pilgrims, Mecca 21955, Saudi Arabia
[34] Al Baha Univ, Fac Med, Dept Med Microbiol, Al Baha 4781, Saudi Arabia
[35] Sheikh Khalifa Gen Hosp, Dept Pathol & Lab Med, Umm Al Quwain 499, U Arab Emirates
[36] Mohammed Bin Rashid Univ Med & Hlth Sci, Coll Med, Dept Pathol, Dubai 505055, U Arab Emirates
[37] Eastern Hlth Cluster, Infect Prevent & Control, Dammam 32253, Saudi Arabia
[38] InsanCare Grp Sci Studies & Specialized Business, Sci Advisory Council, Riyadh 13313, Saudi Arabia
[39] King Faisal Specialist Hosp & Res Ctr, Dept Med, Jeddah 12713, Saudi Arabia
[40] ICAR Indian Vet Res Inst, Div Pathol, Bareilly 243122, Uttar Pradesh, India
[41] Univ Syiah Kuala, Sch Med, Trop Dis Ctr, Banda Aceh 23111, Indonesia
[42] Univ Syiah Kuala, Sch Med, Dept Microbiol, Banda Aceh 23111, Indonesia
关键词
COVID-19; vaccination; hesitancy; acceptance; prevalence; ACCEPTANCE; WILLINGNESS; HEALTH; ACCEPTABILITY; PHYSICIANS; INTENTION; STUDENTS; RECEIVE;
D O I
10.3390/vaccines10081356
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, and Web of Science. Extraction of the required information was performed for each study. A single-arm meta-analysis was performed to determine the global prevalence of COVID-19 vaccination hesitancy; the potential factors related to vaccine hesitancy were analyzed using a Z-test. A total of 56 articles were included in our analysis. We found that the global prevalence of COVID-19 vaccination hesitancy was 25%. Being a woman, being a 50-year-old or younger, being single, being unemployed, living in a household with five or more individuals, having an educational attainment lower than an undergraduate degree, having a non-healthcare-related job and considering COVID-19 vaccines to be unsafe were associated with a higher risk of vaccination hesitancy. In contrast, living with children at home, maintaining physical distancing norms, having ever tested for COVID-19, and having a history of influenza vaccination in the past few years were associated with a lower risk of hesitancy to COVID-19 vaccination. Our study provides valuable information on COVID-19 vaccination hesitancy, and we recommend special interventions in the sub-populations with increased risk to reduce COVID-19 vaccine hesitancy.
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页数:20
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