Immuno-Oncology biomarkers 2010 and beyond: Perspectives from the iSBTc/SITC biomarker task force

被引：21

作者：

Butterfield, Lisa H. ^{[3
,4
]}

Disis, Mary L. ^{[5
]}

Khleif, Samir N. ^{[6
]}

Balwit, James M. ^{[7
]}

Marincola, Francesco M. ^{[1
,2
]}

机构：

[1] NIH, IDIS, Dept Translat Med, Ctr Clin, Bethesda, MD 20892 USA

[2] NIH, CHI, Bethesda, MD 20892 USA

[3] Univ Pittsburgh, Dept Med, Pittsburgh, PA USA

[4] Univ Pittsburgh, Dept Surg & Immunol, Pittsburgh, PA USA

[5] Univ Washington, Tumor Vaccine Grp, Div Oncol, Seattle, WA 98195 USA

[6] NCI, Canc Vaccine Sect, NIH, Bethesda, MD 20892 USA

[7] Soc Immunotherapy Canc & Execut Director Inc, Milwaukee, WI USA

来源：

JOURNAL OF TRANSLATIONAL MEDICINE | 2010年 / 8卷

关键词：

OVARIAN-CANCER; T-CELLS; SURVIVAL; LYMPHOCYTES;

D O I：

10.1186/1479-5876-8-130

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) hosted a one-day symposium at the National Institutes of Health on September 30, 2010 to address development and application of biomarkers in cancer immunotherapy. The symposium, titled Immuno-Oncology Biomarkers 2010 and Beyond: Perspectives from the iSBTc/SITC Biomarker Task Force, gathered approximately 230 investigators equally from academia, industry and governmental/regulatory agencies from around the globe for panel discussions and presentations on the following topics: 1) immunologic monitoring: standardization and validation of assays; 2) correlation of immunity to biologic activity, clinical response and potency assays; 3) novel methodologies for assessing the immune landscape: clinical utility of novel technologies; and 4) recommendations on incorporation of biomarkers into the clinical arena. The presentations are summarized in this report; additional program information and slides are available online at the iSBTc/SITC website.

引用

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