Palladium-catalyzed addition of alcohol pronucleophiles to alkylidenecyclopropanes

被引：100
作者：
Camacho, DH
Nakamura, I
Saito, S
Yamamoto, Y [1 ]
机构：
[1] Tohoku Univ, Dept Chem, Grad Sch Sci, Sendai, Miyagi 9808578, Japan
[2] Tohoku Univ, Inst Chem React Sci, Sendai, Miyagi 9808578, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 01期
关键词：
D O I：
10.1021/jo001428j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed addition of alcohol pronucleophiles 1 to alkylidenecyclopropane derivatives 2 afforded the corresponding allylic ethers 3 in excellent to moderate yields. Catalyst optimization indicated the Pd(PPh3)(4)-P(o-tolyl)(3) combination as the best system among all catalysts tested. Intramolecular reaction also proceeded smoothly. A plausible mechanism for this catalytic reaction was proposed.
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页码：270 / 275
页数：6
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