Advances in the diagnosis and management of pulmonary aspergillosis
被引:22
作者:
Gao, Yuqing
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机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48202 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48202 USA
Gao, Yuqing
[1
]
Soubani, Ayman
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机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48202 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48202 USA
Soubani, Ayman
[1
]
机构:
[1] Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48202 USA
Aspergillus is a mould that is ubiquitous in nature and may lead to a variety of infectious and allergic diseases depending on the host's immune status or pulmonary structure. Invasive pulmonary aspergillosis occurs primarily in patients with severe immunodeficiency. The significance of this infection has dramatically increased with growing numbers of patients with impaired immune state associated with the management of malignancy, organ transplantation, autoimmune and inflammatory conditions; critically ill patients appear to be at an increased risk as well. The introduction of new noninvasive tests, combined with more effective and better-tolerated antifungal agents, has resulted in lower mortality rates associated with this infection. Chronic pulmonary aspergillosis is a locally invasive disease described in patients with chronic lung disease or mild immunodeficiency. Recently, the European Society for Clinical Microbiology and Infectious Diseases provided a more robust sub-classification of this entity that allows for a straightforward approach to diagnosis and management. Allergic bronchopulmonary aspergillosis, a hypersensitivity reaction to Aspergillus antigens, is generally seen in patients with atopy, asthma or cystic fibrosis. This review provides an update on the evolving epidemiology and risk factors of the major manifestations of Aspergillus lung disease and the clinical manifestations that should prompt the clinician to consider these conditions. It also details the role of noninvasive tests in the diagnosis of Aspergillus related lung diseases and advances in the management of these disorders.
机构:
Postgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Agarwal, R.
Chakrabarti, A.
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h-index: 0
机构:
Postgrad Inst Med Educ & Res, Dept Med Microbiol, Div Med Mycol, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Chakrabarti, A.
Shah, A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Delhi, Vallabhbhai Patel Chest Inst, Dept Pulm Med, New Delhi, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Shah, A.
Gupta, D.
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Gupta, D.
Meis, J. F.
论文数: 0引用数: 0
h-index: 0
机构:
Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands
Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, NL-6525 ED Nijmegen, NetherlandsPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Meis, J. F.
Guleria, R.
论文数: 0引用数: 0
h-index: 0
机构:
All India Inst Med Sci, Dept Internal Med, New Delhi, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Guleria, R.
Moss, R.
论文数: 0引用数: 0
h-index: 0
机构:
Stanford Univ, Dept Pediat, Palo Alto, CA 94304 USAPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Moss, R.
Denning, D. W.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Natl Aspergillosis Ctr, Manchester, Lancs, EnglandPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Agarwal, Ritesh
Aggarwal, Ashutosh N.
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机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Aggarwal, Ashutosh N.
Dhooria, Sahajal
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Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Dhooria, Sahajal
Sehgal, Inderpaul Singh
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Sehgal, Inderpaul Singh
Garg, Mandeep
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Radiodiag & Imaging, Chandigarh, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Garg, Mandeep
Saikia, Biman
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Immunopathol, Chandigarh, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Saikia, Biman
Behera, Digambar
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h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Behera, Digambar
Chakrabarti, Arunaloke
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Med Microbiol, Chandigarh, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Alshabani, Khaled
Haq, Athar
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机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Haq, Athar
Miyakawa, Ryo
论文数: 0引用数: 0
h-index: 0
机构:
St John Hosp & Med Ctr, Dept Pediat, Detroit, MI USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Miyakawa, Ryo
Palla, Mohan
论文数: 0引用数: 0
h-index: 0
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Palla, Mohan
Soubani, Ayman O.
论文数: 0引用数: 0
h-index: 0
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
机构:Beilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Avni, Tomer
Levy, Itzhak
论文数: 0引用数: 0
h-index: 0
机构:
Schneiders Med Ctr, Infect Dis Unit, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Levy, Itzhak
Sprecher, Hannah
论文数: 0引用数: 0
h-index: 0
机构:
Rambam Hlth Care Campus, Microbiol Lab, Haifa, Israel
Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Sprecher, Hannah
Yahav, Dafna
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h-index: 0
机构:Beilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Yahav, Dafna
Leibovici, Leonard
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h-index: 0
机构:
Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Leibovici, Leonard
Paulf, Mical
论文数: 0引用数: 0
h-index: 0
机构:
Beilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
机构:
Postgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Agarwal, R.
Chakrabarti, A.
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res, Dept Med Microbiol, Div Med Mycol, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Chakrabarti, A.
Shah, A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Delhi, Vallabhbhai Patel Chest Inst, Dept Pulm Med, New Delhi, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Shah, A.
Gupta, D.
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Gupta, D.
Meis, J. F.
论文数: 0引用数: 0
h-index: 0
机构:
Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands
Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, NL-6525 ED Nijmegen, NetherlandsPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Meis, J. F.
Guleria, R.
论文数: 0引用数: 0
h-index: 0
机构:
All India Inst Med Sci, Dept Internal Med, New Delhi, IndiaPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Guleria, R.
Moss, R.
论文数: 0引用数: 0
h-index: 0
机构:
Stanford Univ, Dept Pediat, Palo Alto, CA 94304 USAPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
Moss, R.
Denning, D. W.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Natl Aspergillosis Ctr, Manchester, Lancs, EnglandPostgrad Inst Med Educ & Res, Dept Pulm Med, Chandigarh 160012, India
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Agarwal, Ritesh
Aggarwal, Ashutosh N.
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Aggarwal, Ashutosh N.
Dhooria, Sahajal
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Dhooria, Sahajal
Sehgal, Inderpaul Singh
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Sehgal, Inderpaul Singh
Garg, Mandeep
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Radiodiag & Imaging, Chandigarh, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Garg, Mandeep
Saikia, Biman
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Immunopathol, Chandigarh, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Saikia, Biman
Behera, Digambar
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
Behera, Digambar
Chakrabarti, Arunaloke
论文数: 0引用数: 0
h-index: 0
机构:
Postgrad Inst Med Educ & Res PGIMER, Dept Med Microbiol, Chandigarh, IndiaPostgrad Inst Med Educ & Res PGIMER, Dept Pulm Med, Chandigarh 160012, India
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Alshabani, Khaled
Haq, Athar
论文数: 0引用数: 0
h-index: 0
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Haq, Athar
Miyakawa, Ryo
论文数: 0引用数: 0
h-index: 0
机构:
St John Hosp & Med Ctr, Dept Pediat, Detroit, MI USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Miyakawa, Ryo
Palla, Mohan
论文数: 0引用数: 0
h-index: 0
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
Palla, Mohan
Soubani, Ayman O.
论文数: 0引用数: 0
h-index: 0
机构:
Wayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USAWayne State Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Detroit, MI 48201 USA
机构:Beilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Avni, Tomer
Levy, Itzhak
论文数: 0引用数: 0
h-index: 0
机构:
Schneiders Med Ctr, Infect Dis Unit, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Levy, Itzhak
Sprecher, Hannah
论文数: 0引用数: 0
h-index: 0
机构:
Rambam Hlth Care Campus, Microbiol Lab, Haifa, Israel
Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Sprecher, Hannah
Yahav, Dafna
论文数: 0引用数: 0
h-index: 0
机构:Beilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Yahav, Dafna
Leibovici, Leonard
论文数: 0引用数: 0
h-index: 0
机构:
Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Leibovici, Leonard
Paulf, Mical
论文数: 0引用数: 0
h-index: 0
机构:
Beilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, Ramat Aviv, IsraelBeilinson Med Ctr, Infect Dis Unit, Rabin Med Ctr, Petah Tiqwa, Israel