Actinomycete-like proteasomes in a Gram-negative bacterium

被引：22
|
作者：
De Mot, Rene [1 ]
机构：
[1] Katholieke Univ Leuven, Fac Biosci Engn, Ctr Microbial & Plant Genet, Dept Microbial & Mol Syst, B-3001 Heverlee, Belgium
来源：
TRENDS IN MICROBIOLOGY | 2007年 / 15卷 / 08期
关键词：
D O I：
10.1016/j.tim.2007.06.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cultivation-independent proteogenomic exploration of mine-drainage biofilm has revealed proteasomes in Gram-negative bacteria of the Nitrospirae phylum (Leptospirillum group 11) dominating this acidophilic community. Most probably, the proteasome genes were acquired from actinobacteria, the only eubacteria previously known to contain proteasomes. In addition, this study shows that the proteasome and the evolutionarily related ATP-dependent protease HsIVU (also known as CIpQY) are not mutually exclusive in prokaryotes.
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页码：335 / 338
页数：4
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