A naked-eye colorimetric sensor for Hg2+ monitoring with cascade signal amplification based on target-induced conjunction of split DNAzyme fragments

被引:51
作者
Chen, Junhua [1 ]
Pan, Jiafeng [1 ]
Chen, Shu [1 ]
机构
[1] Guangdong Inst Ecoenvironm Sci & Technol, Guangdong Key Lab Integrated Agroenvironm Pollut, Guangzhou 510650, Guangdong, Peoples R China
关键词
HYBRIDIZATION CHAIN-REACTION; EXONUCLEASE III ACTIVITY; CATALYTIC NUCLEIC-ACIDS; GOLD NANOPARTICLES; LABEL-FREE; MERCURY ION; CYCLIC AMPLIFICATION; SELECTIVE DETECTION; COMPUTING CIRCUITS; VISUAL DETECTION;
D O I
10.1039/c7cc05445a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A colorimetric sensor for the visual detection of Hg2+ with cascade signal amplification has been successfully constructed using split DNAzyme subunits as sensing elements and gold nanoparticles as signal reporters. The biosensor is ultrasensitive, enabling the visual detection of trace levels of Hg2+ as low as 10 pM without instrumentation.
引用
收藏
页码:10224 / 10227
页数:4
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