Use of cyclosporin in the treatment of steroid resistant post-keratoplasty atopic sclerokeratitis

被引：10

作者：

Daniell, MD

Dart, JKG

Lightman, S

机构：

[1] Moorfields Eye Hosp, London EC1V 2PD, England

[2] Royal Victorian Eye & Ear Hosp, Corneal Serv, Melbourne, Vic 3002, Australia

[3] Inst Ophthalmol, London EC1V 9EL, England

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 2001年 / 85卷 / 01期

关键词：

D O I：

10.1136/bjo.85.1.91

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Aims-To demonstrate that oral cyclosporin is successful in the management of steroid refractory post-keratoplasty atopic sclerokeratitis (PKAS). Methods-Series of three patients. Results-The patients developed PKAS between 2 and 11 days after surgery. All cases failed to respond to oral prednisolone 60-80 mg daily for 10-30 days but resolved with the addition of systemic cyclosporin 5.0-7.5 mg/kg/day. There have been no relapses following withdrawal of therapy after 3-18 months. Conclusions-PKAS is an uncommon, but severe, complication of corneal graft surgery and often responds to oral prednisolone treatment. Oral cyclosporin results in rapid resolution of PKAS in steroid unresponsive cases.

引用

页码：91 / 92

页数：2

共 11 条

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[2]

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