Fulminant hepatic failure secondary to erlotinib

被引:36
作者
Liu, Weitian [1 ]
Makrauer, Frederick L.
Qamar, Amir A.
Jaenne, Pasi A.
Odze, Robert D.
机构
[1] Harvard Univ, Sch Med, Div Gastroenterol Hepatol & Endoscopy, Brigham & Womens Hosp, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Dana Farber Brigham & Womens Hosp Canc Ctr, Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
D O I
10.1016/j.cgh.2007.04.014
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Erlotinib is a tyrosine kinase inhibitor recently approved by the Food and Drug Administration for the treatment of non-small-cell lung cancer and pancreatic cancer. We report a case of a patient with stage IV non-small-cell lung cancer who died of fulminant hepatic failure as a result of treatment with erlotinib.
引用
收藏
页码:917 / 920
页数:4
相关论文
共 24 条
[1]   Dermatologic side effects associated with the epidermal growth factor receptor inhibitors [J].
Agero, Anna Liza C. ;
Dusza, Stephen W. ;
Benvenuto-Andrade, Cristiane ;
Busam, Klaus J. ;
Myskowski, Patricia ;
Halpern, Allan C. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2006, 55 (04) :657-670
[2]   FDA drug approval summary:: Gefitinib (ZD1839) (Iressa®) tablets [J].
Cohen, MH ;
Williams, GA ;
Sridhara, R ;
Chen, G ;
Pazdur, R .
ONCOLOGIST, 2003, 8 (04) :303-306
[3]   INHIBITION OF MITOCHONDRIAL BETA-OXIDATION AS A MECHANISM OF HEPATOTOXICITY [J].
FROMENTY, B ;
PESSAYRE, D .
PHARMACOLOGY & THERAPEUTICS, 1995, 67 (01) :101-154
[4]   Erlotinib: Optimizing therapy with predictors of response? [J].
Goodin, Susan .
CLINICAL CANCER RESEARCH, 2006, 12 (10) :2961-2963
[5]   TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer [J].
Herbst, RS ;
Prager, D ;
Hermann, R ;
Fehrenbacher, L ;
Johnson, BE ;
Sandler, A ;
Kris, MG ;
Tran, HT ;
Klein, P ;
Li, X ;
Ramies, D ;
Johnson, DH ;
Miller, VA .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (25) :5892-5899
[6]   Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies [J].
Hidalgo, M ;
Siu, LL ;
Nemunaitis, J ;
Rizzo, J ;
Hammond, LA ;
Takimoto, C ;
Eckhardt, SG ;
Tolcher, A ;
Britten, CD ;
Denis, L ;
Ferrante, K ;
Von Hoff, DD ;
Silberman, S ;
Rowinsky, EK .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (13) :3267-3279
[7]   Pharmacokinetics and pharmacodynamics: Maximizing the clinical potential of erlotinib (Tarceva) [J].
Hidalgo, M ;
Bloedow, D .
SEMINARS IN ONCOLOGY, 2003, 30 (03) :25-33
[8]   Side effects related to cancer treatment - Case 1. Hepatitis following treatment with gefitinib [J].
Ho, C ;
Davis, J ;
Anderson, F ;
Bebb, G ;
Murray, N .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (33) :8531-8533
[9]   Forum - Mechanisms of hepatotoxicity [J].
Jaeschke, H ;
Gores, GJ ;
Cederbaum, AI ;
Hinson, JA ;
Pessayre, D ;
Lemasters, JJ .
TOXICOLOGICAL SCIENCES, 2002, 65 (02) :166-176
[10]   Drug-induced liver injury [J].
Kaplowitz, N .
CLINICAL INFECTIOUS DISEASES, 2004, 38 :S44-S48