Impact of feedback from pharmacists in reducing antipsychotic polypharmacy in schizophrenia

被引:19
作者
Hazra, Monica
Uchida, Hiroyuki [4 ]
Sproule, Beth [2 ,3 ]
Remington, Gary [2 ]
Suzuki, Takefumi [4 ]
Mamo, David C. [1 ,2 ]
机构
[1] Univ Toronto, Multimodal Imaging Grp, Ctr Addict & Mental Hlth, Toronto, ON M5T 1R8, Canada
[2] Univ Toronto, Dept Psychiat, Toronto, ON M5T 1R8, Canada
[3] Univ Toronto, Fac Pharm, Toronto, ON M5T 1R8, Canada
[4] Keio Univ, Sch Med, Dept Neuropsychiat, Tokyo, Japan
关键词
antipsychotic; monitoring; polypharmacy; prescription; schizophrenia; INTERVENTION; KNOWLEDGE;
D O I
10.1111/j.1440-1819.2011.02280.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The objective was to examine effects of active interventions on physician's prescribing of antipsychotic polypharmacy. Prescriptions for patients with schizophrenia at the Centre for Addiction and Mental Health, Canada were collected in 2006 (n = 648) and 2008 (n = 778). During the intervening period, a pharmacist monitored prescriptions with antipsychotic polypharmacy and contacted corresponding prescribers to provide education on risks of polypharmacy. Moreover, educational sessions on polypharmacy were presented to inpatient and outpatient teams. A three-fold decrease in the prevalence of antipsychotic polypharmacy was observed between 2006 (18.3%) and 2008 (6.6%). Thus, active monitoring of prescriptions with educational interventions could reduce antipsychotic polypharmacy.
引用
收藏
页码:676 / 678
页数:3
相关论文
共 7 条
[1]   Evaluation of a multifaceted intervention to limit excessive antipsychotic co-prescribing in schizophrenia out-patients [J].
Baandrup, L. ;
Allerup, P. ;
Lublin, H. ;
Nordentoft, M. ;
Peacock, L. ;
Glenthoj, B. .
ACTA PSYCHIATRICA SCANDINAVICA, 2010, 122 (05) :367-374
[2]   Public knowledge, public trust: Understanding the 'knowledge deficit' [J].
Brunk, Conrad G. .
COMMUNITY GENETICS, 2006, 9 (03) :178-183
[3]  
LASKA E, 1980, ARCH GEN PSYCHIAT, V37, P824
[4]  
Ozdemir Vural, 2011, Current Pharmacogenomics & Personalized Medicine, V9, P1
[5]   Polypharmacy with Second-Generation Antipsychotics: A Review of Evidence [J].
Pandurangi, Anand K. ;
Dalkilic, Alican .
JOURNAL OF PSYCHIATRIC PRACTICE, 2008, 14 (06) :345-367
[6]  
Robertson Jane, 2010, Int J Pharm Pract, V18, P69
[7]   The DEBIT trial: an intervention to reduce antipsychotic polypharmacy prescribing in adult psychiatry wards - a cluster randomized controlled trial [J].
Thompson, A. ;
Sullivan, S. A. ;
Barley, M. ;
Strange, S. A. ;
Moore, L. ;
Rogers, P. ;
Sipos, A. ;
Harrison, G. .
PSYCHOLOGICAL MEDICINE, 2008, 38 (05) :705-715