Samarium-catalyzed tandem semipinacol rearrangement/Tishchenko reaction of α-hydroxy epoxides:: A novel approach to highly stereoselective construction of 2-quaternary 1,3-diol units

被引：0
|
作者：
Fan, CA
Wang, BM
Tu, YQ [1 ]
Song, ZL
机构：
[1] Lanzhou Univ, Dept Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2001年 / 40卷 / 20期
关键词：
alcohols; diastereoselectivity; rearrangement; samarium;
D O I：
10.1002/1521-3773(20011015)40:20<3877::AID-ANIE3877>3.0.CO;2-S
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three contiguous stereocenters are constructed with high diastereoselectivity in a novel samarium-catalyzed tandem reaction of α-hydroxy epoxides 1 to give exclusively the C1,C2-anti isomers of 2 and 2′. This could lead to the development of a general procedure for the diastereoselective construction of 2-quaternary 1,3-diol units.
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页码：3877 / +
页数：5
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