Considerations for Peripheral Blood Stem Cell Apheresis in a Low Body Weight Infant

被引：2
作者：
Singh, Suvir [1 ]
Kakkar, Shruti [2 ]
Singh, Karambir [3 ]
Kumar, Rajesh [4 ]
Gupta, Sonia [4 ]
机构：
[1] Dept Clin Hematol & Stem Cell Transplantat, Ludhiana, Punjab, India
[2] Dept Pediat Oncol, Ludhiana, Punjab, India
[3] Dept Pediat Crit Care, Ludhiana, Punjab, India
[4] Dept Transfus Med & Immunohematol, Ludhiana, Punjab, India
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2022年 / 44卷 / 03期
关键词：
infant; transplant; neuroblastoma; economic; pediatrics; EXPERIENCE; COLLECTION; NEUROBLASTOMA; EFFICACY; SAFETY;
D O I：
10.1097/MPH.0000000000002380
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Introduction: Peripheral blood stem cell (PBSC) apheresis in infants (<10 kg body weight) requires specific precautions to prevent periprocedural complications. Case Report: A 9 month old child was diagnosed with high-risk neuroblastoma and planned for autologous stem cell transplantation after induction chemotherapy. We illustrate the precautions and technical details observed while performing PBSC collection in this patient. Discussion: Use of continuous flow devices, priming of apheresis circuits, appropriate flow rates and continuous monitoring can help to mitigate several procedure related complications. Conclusions: PBSC apheresis in infants (<10 Kg) is safe and feasible with appropriate precautions detailed above.
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收藏
页码：E816 / E818
页数：3
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