Green protocol for the Friedlander synthesis:: KAl(SO4)2•12H2O-SiO2 (Alum-SiO2) a highly efficient catalyst in the synthesis of quinolines

被引：0

作者：

Mohammadi, Ali A. ^{[1
]}

Azizian, Javad ^{[1
]}

Hadadzahmatkesh, Armin ^{[1
]}

Asghariganjeh, Mohammad R. ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, Fac Sci, Tehran, Iran

来源：

HETEROCYCLES | 2008年 / 75卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this letter, an efficient synthesis of an array of poly-substituted quinolines from 2-aminoaryl ketones and beta-ketoester, beta-diketones and alpha-methylene ketones using KA1(SO4)(2)center dot 12H(2)O-SiO2 (Alum-SiO2) under solvent-free conditions is described. Compared with the classical Friedlander synthesis this new synthetic method has the advantage of excellent yields (90-98%), shorter reaction time, and reusability of the catalyst.

引用

页码：947 / 954

页数：8

共 25 条

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