Spinal Cord MRI in Multiple Sclerosis

被引:17
作者
Muccilli, Alexandra [1 ,2 ]
Seyman, Estelle [1 ]
Oh, Jiwon [1 ,3 ]
机构
[1] Univ Toronto, St Michaels Hosp, Div Neurol, 30 Bond St, Toronto, ON M5B 1W8, Canada
[2] Univ Montreal, CHU Montreal, Div Neurol, 1058 St Denis St, Montreal, PQ H2X 3J4, Canada
[3] Johns Hopkins Univ, Dept Neurol, Baltimore, MD 21218 USA
关键词
Spinal cord; MRI; Multiple sclerosis; Clinical usefulness; Prediction; Quantitative techniques; CLINICALLY ISOLATED SYNDROMES; T1; INVERSION-RECOVERY; ANISOTROPIC WATER DIFFUSION; UPPER CERVICAL CORD; IN-VIVO ASSESSMENT; MAGNETIZATION-TRANSFER; RELAPSE-ONSET; FOLLOW-UP; LEPTOMENINGEAL INFLAMMATION; MENINGEAL INFLAMMATION;
D O I
10.1016/j.ncl.2017.08.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Spinal cord (SC) MRI in multiple sclerosis (MS) has significant usefulness in clinical and investigational settings. Conventional MRI of the SC is used in clinical practice, because it has both diagnostic and prognostic value. A number of advanced, quantitative SC MRI measures that assess the structural and functional integrity of the SC have been evaluated in investigational settings. These techniques have collectively demonstrated usefulness in providing insight into microstructural and functional changes relevant to disability in MS. With further development, these techniques may be useful in clinical trial settings as biomarkers of neurodegeneration and protection, and in day-to-day clinical practice,
引用
收藏
页码:35 / +
页数:24
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