Spinal Cord MRI in Multiple Sclerosis

被引：17

作者：

Muccilli, Alexandra ^{[1
,2
]}

Seyman, Estelle ^{[1
]}

Oh, Jiwon ^{[1
,3
]}

机构：

[1] Univ Toronto, St Michaels Hosp, Div Neurol, 30 Bond St, Toronto, ON M5B 1W8, Canada

[2] Univ Montreal, CHU Montreal, Div Neurol, 1058 St Denis St, Montreal, PQ H2X 3J4, Canada

[3] Johns Hopkins Univ, Dept Neurol, Baltimore, MD 21218 USA

来源：

NEUROLOGIC CLINICS | 2018年 / 36卷 / 01期

关键词：

Spinal cord; MRI; Multiple sclerosis; Clinical usefulness; Prediction; Quantitative techniques; CLINICALLY ISOLATED SYNDROMES; T1; INVERSION-RECOVERY; ANISOTROPIC WATER DIFFUSION; UPPER CERVICAL CORD; IN-VIVO ASSESSMENT; MAGNETIZATION-TRANSFER; RELAPSE-ONSET; FOLLOW-UP; LEPTOMENINGEAL INFLAMMATION; MENINGEAL INFLAMMATION;

D O I：

10.1016/j.ncl.2017.08.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Spinal cord (SC) MRI in multiple sclerosis (MS) has significant usefulness in clinical and investigational settings. Conventional MRI of the SC is used in clinical practice, because it has both diagnostic and prognostic value. A number of advanced, quantitative SC MRI measures that assess the structural and functional integrity of the SC have been evaluated in investigational settings. These techniques have collectively demonstrated usefulness in providing insight into microstructural and functional changes relevant to disability in MS. With further development, these techniques may be useful in clinical trial settings as biomarkers of neurodegeneration and protection, and in day-to-day clinical practice,

引用

页码：35 / +

页数：24

共 150 条

[1] Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis [J].

Absinta, Martina ;

Vuolo, Luisa ;

Rao, Anuradha ;

Nair, Govind ;

Sati, Pascal ;

Cortese, Irene C. M. ;

Ohayon, Joan ;

Fenton, Kaylan ;

Reyes-Mantilla, Maria I. ;

Maric, Dragan ;

Calabresi, Peter A. ;

Butman, John A. ;

Pardo, Carlos A. ;

Reich, Daniel S. .

NEUROLOGY, 2015, 85 (01) :18-28

[2] Seven-Tesla Phase Imaging of Acute Multiple Sclerosis Lesions: A New Window into the Inflammatory Process [J].

Absinta, Martina ;

Sati, Pascal ;

Gaitan, Maria I. ;

Maggi, Pietro ;

Cortese, Irene C. M. ;

Filippi, Massimo ;

Reich, Daniel S. .

ANNALS OF NEUROLOGY, 2013, 74 (05) :669-678

[3] Evidence for enhanced functional activity of cervical cord in relapsing multiple sclerosis [J].

Agosta, F. ;

Valsasina, P. ;

Rocca, M. A. ;

Caputo, D. ;

Sala, S. ;

Judica, E. ;

Stroman, P. W. ;

Filippi, M. .

MAGNETIC RESONANCE IN MEDICINE, 2008, 59 (05) :1035-1042

[4] In vivo assessment of cervical cord damage in MS patients: a longitudinal diffusion tensor MRI study [J].

Agosta, F. ;

Absinta, M. ;

Sormani, M. P. ;

Ghezzi, A. ;

Bertolotto, A. ;

Montanari, E. ;

Comi, G. ;

Filippi, M. .

BRAIN, 2007, 130 :2211-2219

[5] Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI [J].

Agosta, F ;

Benedetti, B ;

Rocca, MA ;

Valsasina, P ;

Rovaris, M ;

Comi, G ;

Filippi, M .

NEUROLOGY, 2005, 64 (04) :631-635

[6] Primary Progressive Multiple Sclerosis: Tactile-associated Functional MR Activity in the Cervical Spinal Cord [J].

Agosta, Federica ;

Valsasina, Paola ;

Absinta, Martina ;

Sala, Stefania ;

Caputo, Domenico ;

Filippi, Massimo .

RADIOLOGY, 2009, 253 (01) :209-215

[7] Comparison of Sagittal FSE T2, STIR, and T1-Weighted Phase-Sensitive Inversion Recovery in the Detection of Spinal Cord Lesions in MS at 3T [J].

Alcaide-Leon, P. ;

Pauranik, A. ;

Alshafai, L. ;

Rawal, S. ;

Oh, J. ;

Montanera, W. ;

Leung, G. ;

Bharatha, A. .

AMERICAN JOURNAL OF NEURORADIOLOGY, 2016, 37 (05) :970-975

[8] The clinico-radiological paradox in multiple sclerosis revisited [J].

Barkhof, F .

CURRENT OPINION IN NEUROLOGY, 2002, 15 (03) :239-245

[9] Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis [J].

Barkhof, F ;

Filippi, M ;

Miller, DH ;

Scheltens, P ;

Campi, A ;

Polman, CH ;

Comi, G ;

Ader, HJ ;

Losseff, N ;

Valk, J .

BRAIN, 1997, 120 :2059-2069

[10] Inferring microstructural features and the physiological state of tissues from diffusion-weighted images [J].

Basser, PJ .

NMR IN BIOMEDICINE, 1995, 8 (7-8) :333-344

← 1 2 3 4 5 6 7 8 9 10 →