Discrepancies in the histologic type between biopsy and resected specimens: A cautionary note for mixed-type gastric carcinoma

被引：8

作者：

Komatsu, Shuhei ^{[1
]}

Ichikawa, Daisuke ^{[1
]}

Miyamae, Mahito ^{[1
]}

Kosuga, Toshiyuki ^{[1
]}

Konishi, Hirotaka ^{[1
]}

Shiozaki, Atsushi ^{[1
]}

Fujiwara, Hitoshi ^{[1
]}

Okamoto, Kazuma ^{[1
]}

Kishimoto, Mitsuo ^{[2
]}

Otsuji, Eigo ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Surg, Div Digest Surg, Kamigyo Ku, Kyoto 6028566, Japan

[2] Kyoto Prefectural Univ Med, Dept Surg Pathol, Kamigyo Ku, Kyoto 6028566, Japan

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2015年 / 21卷 / 15期

关键词：

Biopsy; Histologic type; Histologic mixed-type gastric carcinoma; LYMPH-NODE METASTASES; PROGNOSTIC-SIGNIFICANCE; CANCER; GASTRECTOMY; RISK; WELL;

D O I：

10.3748/wjg.v21.i15.4673

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

AIM: To evaluate discrepancies between biopsy and resected specimens using the Japanese Classification of Gastric Carcinoma (JCGC) and tumor-node-metastasis (TNM) classification. METHODS: A total of 376 consecutive paired samples from biopsy and resected gastric specimens, which were derived from curative gastrectomy for gastric cancer between 2008 and 2011, were retrospectively analyzed. RESULTS: (1) Discrepancies in the histologic type were observed between biopsy and resected specimens; 11.7% (44/376) in the JCGC and 18.1% (68/376) in TNM. In specimens diagnosed as the differentiated type from biopsy specimens, 14.4% (28/195) in the JCGC and 41.1% (67/163) in TNM were finally diagnosed as the undifferentiated type from resected specimens; and (2) the incidence of mixed-type gastric cancer was significantly higher in specimens with discrepancies than in those without in both the JCGC and TNM (both P < 0.0001); 93.2% (41/44) of specimens with discrepancies in the JCGC and 97.1% (66/68) of specimens with discrepancies in TNM were mixed-type gastric cancers. CONCLUSION: Mixed-type gastric cancer was associated with a high incidence of histologic discrepancies between biopsy and resected specimens in both the JCGC and TNM definitions. Care should be taken in deciding treatments based on diagnosis of the histologic type for mixed-type gastric cancer from biopsy specimens.

引用

页码：4673 / 4679

页数：7

共 27 条

[21]

Sobin L. H., 2010, TNM Classification of Malignant Tumours, V7th

[22]

Tahara E, 1996, SEMIN ONCOL, V23, P307

[23] Risk Factors for Lymph Node Metastasis from Gastric Cancers with Submucosal Invasion [J].

Tajima, Yusuke ;

Murakami, Masahiko ;

Yamazaki, Kimiyasu ;

Masuda, Yuki ;

Aoki, Shigeo ;

Kato, Masanori ;

Sato, Atsushi ;

Goto, Satoru ;

Otsuka, Koji ;

Kato, Takashi .

ANNALS OF SURGICAL ONCOLOGY, 2010, 17 (06) :1597-1604

[24] Discrepancies in histologic diagnoses of early gastric cancer between biopsy and endoscopic mucosal resection specimens [J].

Takao, Madoka ;

Kakushima, Naomi ;

Takizawa, Kohei ;

Tanaka, Masaki ;

Yamaguchi, Yuichiro ;

Matsubayashi, Hiroyuki ;

Kusafuka, Kimihide ;

Ono, Hiroyuki .

GASTRIC CANCER, 2012, 15 (01) :91-96

[25] Risk of lymph node metastases from intramucosal gastric cancer in relation to histological types: how to manage the mixed histological type for endoscopic submucosal dissection [J].

Takizawa, Kohei ;

Ono, Hiroyuki ;

Kakushima, Naomi ;

Tanaka, Masaki ;

Hasuike, Noriaki ;

Matsubayashi, Hiroyuki ;

Yamagichi, Yuichiro ;

Bando, Etsuro ;

Terashima, Masanori ;

Kusafuka, Kimihide ;

Nakajima, Takashi .

GASTRIC CANCER, 2013, 16 (04) :531-536

[26]

Tanabe H, 2007, STOM INT, V42, P1561

[27]

Watanabe G, 2007, STOM INT, V42, P1577

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