INVESTIGATION OF APOPTOSIS IN NORMAL AND LEUKEMIC CELLS INDUCED BY X-RAY IRRADIATION

被引：0
作者：
Nevoie, A. [1 ]
Pascariu, M. [1 ]
Jitaru, D. [2 ]
Ivanov, I. [2 ,3 ]
Constantinescu, D. [2 ,4 ]
Carasevici, E. [2 ,3 ]
Luchian, T. [1 ]
机构：
[1] Alexandru Ioan Cuza Univ, Fac Phys, Iasi, Romania
[2] Hosp St Spiridon, Lab Immunol & Genet, Iasi, Romania
[3] Univ Med & Pharm Gr T Popa, Iasi, Romania
[4] Inst Publ Hlth, Iasi, Romania
来源：
DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES | 2011年 / 6卷 / 01期
关键词：
Normal mononuclear cell; Leukemia cell line; X-ray; Apoptosis; Dose rate; ACUTE NONLYMPHOBLASTIC LEUKEMIA; MARROW TRANSPLANTATION; 1ST REMISSION; RESPONSES;
D O I：
暂无
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
The aim of this work is the stydy of the functional changes of normal and leukemic cells exposed to X radiation. Normal mononuclear cells and two human leukemia cell lines (Jurkat and K562) were used for this study. The cells have been grown in the same medium and same conditions. To irradiate the human cells cultures, different doses were used. The process of programmed cell death, apoptosis, has been analyzed using the flow cytometry technique at 3, 24, 48 and 72 hours from irradiation. After 72 hours after the irradiation, the cells show the characteristic signs of apoptosis.
引用
收藏
页码：259 / 264
页数：6
相关论文
共 50 条
  • [31] Predicting the clonogenic survival of A549 cells after modulated x-ray irradiation using the linear quadratic model
    Bromley, Regina
    Oliver, Lyn
    Davey, Ross
    Harvie, Rozelle
    Baldock, Clive
    PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (02) : 187 - 206
  • [32] Influence of x-ray irradiation on doped europium in BaMgAl10O17 studied by x-ray absorption fine structure and x-ray diffraction
    Hirosawa, I
    Honma, T
    Kato, K
    Kijima, N
    Shimomura, Y
    JOURNAL OF THE SOCIETY FOR INFORMATION DISPLAY, 2005, 13 (08) : 673 - 678
  • [33] Aloe vera modulates X-ray induced hematological and splenic tissue damage in mice
    Bala, S.
    Chugh, N. A.
    Bansal, S. C.
    Koul, A.
    HUMAN & EXPERIMENTAL TOXICOLOGY, 2019, 38 (10) : 1195 - 1211
  • [34] X-ray interferometric investigation of homogeneity of substances
    Drmeyan, HR
    CRYSTAL RESEARCH AND TECHNOLOGY, 2003, 38 (06) : 450 - 456
  • [35] STRUCTURAL CHANGES IN POROUS Si INDUCED BY HIGH ENERGY ELECTRON AND X-RAY PHOTONS IRRADIATION
    Mockeviciene, S.
    Prosycevas, I.
    Adliene, D.
    Baltusnikas, A.
    Kaciulyte, Vaida
    Pikaite, Rita
    3RD INTERNATIONAL CONFERENCE RADIATION INTERACTION WITH MATERIAL AND ITS USE IN TECHNOLOGIES 2010, 2010, : 296 - 299
  • [36] Impacts of X-ray irradiation on Saccharomyces cerevisiae cells growth and physiological-biochemical characteristic
    Cao Guo-Zhen
    Zhang Miao-Miao
    Li Wen-Jian
    Miao Jian-Shun
    Lu Dong
    Zhang Wen-De
    NUCLEAR SCIENCE AND TECHNIQUES, 2015, 26 (06)
  • [37] Comparison of X-ray vs. gamma irradiation of CPDA-1 red cells
    Janatpour, K
    Denning, L
    Nelson, K
    Betlach, B
    MacKenzie, M
    Holland, P
    VOX SANGUINIS, 2005, 89 (04) : 215 - 219
  • [38] MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells
    Sun, Lue
    Morikawa, Kumi
    Sogo, Yu
    Sugiura, Yuki
    JOURNAL OF RADIATION RESEARCH, 2021, 62 (05) : 782 - 792
  • [39] Different cell cycle mechanisms between UV-induced and X-ray-induced apoptosis in WiDr colorectal carcinoma cells
    K. Iwamoto
    N. Shinomiya
    H. Mochizuki
    Apoptosis, 1999, 4 : 59 - 66
  • [40] Different cell cycle mechanisms between UV-induced and X-ray-induced apoptosis in WiDr colorectal carcinoma cells
    Iwamoto, K
    Shinomiya, N
    Mochizuki, H
    APOPTOSIS, 1999, 4 (01) : 59 - 66
12345