Cyclic Peptides for the Treatment of Cancers: A Review

被引：41
作者：
Ramadhani, Dalifa [1 ]
Maharani, Rani [2 ]
Gazzali, Amirah Mohd [3 ]
Muchtaridi, Muchtaridi [1 ]
机构：
[1] Univ Padjadjaran, Fac Pharm, Dept Pharmaceut Anal & Med Chem, Jl Raya Bandung Sumedang Km 21, Sumedang 45363, Indonesia
[2] Univ Padjadjaran, Fac Math & Nat Sci, Dept Chem, Jatinangor 45363, Indonesia
[3] Univ Sains Malaysia, Sch Pharmaceut Sci, George Town 11800, Malaysia
来源：
MOLECULES | 2022年 / 27卷 / 14期
关键词：
anticancer; cyclic peptide; mechanism of anticancer; in vitro; in vivo; MITOCHONDRIA-MEDIATED APOPTOSIS; NEW-GUINEA COLLECTION; HUMAN BREAST-CANCER; STRUCTURAL-CHARACTERIZATION; BIOLOGICAL EVALUATION; CELL-PERMEABILITY; HUMAN PROSTATE; MARINE FUNGUS; KAHALALIDE-F; B-D;
D O I：
10.3390/molecules27144428
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cyclic peptides have been widely reported to have therapeutic abilities in the treatment of cancer. This has been proven through in vitro and in vivo studies against breast, lung, liver, colon, and prostate cancers, among others. The multitude of data available in the literature supports the potential of cyclic peptides as anticancer agents. This review summarizes the findings from previously reported studies and discusses the different cyclic peptide compounds, the sources, and their modes of action as anticancer agents. The prospects and future of cyclic peptides will also be described to give an overview on the direction of cyclic peptide development for clinical applications.
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页数：28
相关论文
共 125 条
[11]   A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells [J].
Birts, Charles N. ;
Nijjar, Sharandip K. ;
Mardle, Charlotte A. ;
Hoakwie, Franciane ;
Duriez, Patrick J. ;
Blaydes, Jeremy P. ;
Tavassoli, Ali .
CHEMICAL SCIENCE, 2013, 4 (08) :3046-3057
[12]  
Bonnington LS, 2018, NAT PROD COMMUN, V13, P1287
[13]   Cupolamide A: A cytotoxic cyclic heptapeptide from two samples of the sponge Theonella cupola [J].
Bonnington, LS ;
Tanaka, J ;
Higa, T ;
Kimura, J ;
Yoshimura, Y ;
Nakao, Y ;
Yoshida, WY ;
Scheuer, PJ .
JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (22) :7765-7767
[14]   Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds [J].
Chan, Lai Y. ;
Gunasekera, Sunithi ;
Henriques, Sonia T. ;
Worth, Nathalie F. ;
Le, Sarah-Jane ;
Clark, Richard J. ;
Campbell, Julie H. ;
Craik, David J. ;
Daly, Norelle L. .
BLOOD, 2011, 118 (25) :6709-6717
[15]   Synthesis and biological evaluation of cyclopeptide GG-8-6 and its analogues as anti-hepatocellular carcinoma agents [J].
Chen, Jie-Tao ;
Ma, Ru ;
Sun, Shi-Chang ;
Zhu, Xiao-Feng ;
Xu, Xiao-Li ;
Mu, Qing .
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 26 (03) :609-622
[16]   First total synthesis of cyclodepsipeptides clavatustide A and B and their enantiomers [J].
Chettu, Suresh Kumar ;
Madhu, Rajesh Bagepalli ;
Raolji, Gajendrasinh Balvantsinh ;
Babu, Korupolu Raghu ;
Rao, N. S. Kameswara ;
Gopalakrishnan, Srividya ;
Ismail, Ayesha ;
Reddy, G. Bhanuprakash ;
Shafi, Syed .
RSC ADVANCES, 2016, 6 (66) :61555-61565
[17]   Apolipoprotein E and Peptide Mimetics Modulate Inflammation by Binding the SET Protein and Activating Protein Phosphatase 2A [J].
Christensen, Dale J. ;
Ohkubo, Nobutaka ;
Oddo, Jessica ;
Van Kanegan, Michael J. ;
Neil, Jessica ;
Li, Fengqiao ;
Colton, Carol A. ;
Vitek, Michael P. .
JOURNAL OF IMMUNOLOGY, 2011, 186 (04) :2535-2542
[18]   The role of αvβ3 in prostate cancer progression [J].
Cooper, CR ;
Chay, CH ;
Pienta, KJ .
NEOPLASIA, 2002, 4 (03) :191-194
[19]   IB-01212, a new cytotoxic cyclodepsipeptide isolated from the marine fungus Clonostachys sp ESNA-A009 [J].
Cruz, LJ ;
Insua, MM ;
Baz, JP ;
Trujillo, M ;
Rodriguez-Mias, RA ;
Oliveira, E ;
Giralt, E ;
Albericio, F ;
Cañedo, LM .
JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (09) :3335-3338
[20]   Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer [J].
D'Souza, Charlotte ;
Henriques, Sonia Troeira ;
Wang, Conan K. ;
Cheneval, Olivier ;
Chan, Lai Yue ;
Bokil, Nilesh J. ;
Sweet, Matthew J. ;
Craik, David J. .
BIOCHEMISTRY, 2016, 55 (02) :396-405
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