Cyclic Peptides for the Treatment of Cancers: A Review

被引：41
作者：
Ramadhani, Dalifa [1 ]
Maharani, Rani [2 ]
Gazzali, Amirah Mohd [3 ]
Muchtaridi, Muchtaridi [1 ]
机构：
[1] Univ Padjadjaran, Fac Pharm, Dept Pharmaceut Anal & Med Chem, Jl Raya Bandung Sumedang Km 21, Sumedang 45363, Indonesia
[2] Univ Padjadjaran, Fac Math & Nat Sci, Dept Chem, Jatinangor 45363, Indonesia
[3] Univ Sains Malaysia, Sch Pharmaceut Sci, George Town 11800, Malaysia
来源：
MOLECULES | 2022年 / 27卷 / 14期
关键词：
anticancer; cyclic peptide; mechanism of anticancer; in vitro; in vivo; MITOCHONDRIA-MEDIATED APOPTOSIS; NEW-GUINEA COLLECTION; HUMAN BREAST-CANCER; STRUCTURAL-CHARACTERIZATION; BIOLOGICAL EVALUATION; CELL-PERMEABILITY; HUMAN PROSTATE; MARINE FUNGUS; KAHALALIDE-F; B-D;
D O I：
10.3390/molecules27144428
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cyclic peptides have been widely reported to have therapeutic abilities in the treatment of cancer. This has been proven through in vitro and in vivo studies against breast, lung, liver, colon, and prostate cancers, among others. The multitude of data available in the literature supports the potential of cyclic peptides as anticancer agents. This review summarizes the findings from previously reported studies and discusses the different cyclic peptide compounds, the sources, and their modes of action as anticancer agents. The prospects and future of cyclic peptides will also be described to give an overview on the direction of cyclic peptide development for clinical applications.
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页数：28
相关论文
共 125 条
[1]   Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review [J].
Abdalla, Muna Ali ;
McGaw, Lyndy J. .
MOLECULES, 2018, 23 (08)
[2]   Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action [J].
Akbarian, Mohsen ;
Khani, Ali ;
Eghbalpour, Sara ;
Uversky, Vladimir N. .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (03)
[3]   Methods and Protocols of modern solid phase peptide synthesis [J].
Amblard, M ;
Fehrentz, JA ;
Martinez, J ;
Subra, G .
MOLECULAR BIOTECHNOLOGY, 2006, 33 (03) :239-254
[4]   An α-fetoprotein-derived peptide reduces the uterine hyperplasia and increases the antitumour effect of tamoxifen [J].
Andersen, T. T. ;
Georgekutty, J. ;
DeFreest, L. A. ;
Amaratunga, G. ;
Narendran, A. ;
Lemanski, N. ;
Jacobson, H. I. ;
Bennett, J. A. .
BRITISH JOURNAL OF CANCER, 2007, 97 (03) :327-333
[5]   ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics [J].
Arteaga, Carlos L. ;
Engelman, Jeffrey A. .
CANCER CELL, 2014, 25 (03) :282-303
[6]   Cancer-associated fibroblasts lead tumor invasion through integrin-β3-dependent fibronectin assembly [J].
Attieh, Youmna ;
Clark, Andrew G. ;
Grass, Carina ;
Richon, Sophie ;
Pocard, Marc ;
Mariani, Pascale ;
Elkhatib, Nadia ;
Betz, Timo ;
Gurchenkov, Basile ;
Vignjevic, Danijela Matic .
JOURNAL OF CELL BIOLOGY, 2017, 216 (11) :3509-3520
[7]   Anti-Cancer Effects of Cyclic Peptide ALOS4 in a Human Melanoma Mouse Model [J].
Bar Levi ;
Yacobovich, Shiri ;
Kirby, Michael ;
Becker, Maria ;
Agranyoni, Oryan ;
Redko, Boris ;
Gellerman, Gary ;
Pinhasov, Albert ;
Koman, Igor ;
Nesher, Elimelech .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (17)
[8]   αvβ3 and αvβ5 integrin expression in glioma periphery [J].
Bello, L ;
Francolini, M ;
Marthyn, P ;
Zhang, JP ;
Carroll, RS ;
Nikas, DC ;
Strasser, JF ;
Villani, R ;
Cheresh, DA ;
Black, PM .
NEUROSURGERY, 2001, 49 (02) :380-389
[9]   Sansalvamide: A new cytotoxic cyclic depsipeptide produced by a marine fungus of the genus Fusarium [J].
Belofsky, GN ;
Jensen, PR ;
Fenical, W .
TETRAHEDRON LETTERS, 1999, 40 (15) :2913-2916
[10]   AFPep: an anti-breast cancer peptide that is orally active [J].
Bennett, James A. ;
DeFreest, Lori ;
Anaka, Ikenna ;
Saadati, Hamid ;
Balulad, Sujata ;
Jacobson, Herbert I. ;
Andersen, Thomas T. .
BREAST CANCER RESEARCH AND TREATMENT, 2006, 98 (02) :133-141
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