Recent advances of Sterculia gums uses in drug delivery systems

被引：11
作者：
da Silva, Julia Samara Ferreira [1 ]
Oliveira, Antonio Carla de Jesus [1 ]
Soares, Monica Felts de La Roca [1 ]
Soares-Sobrinho, Jose Lamartine [1 ]
机构：
[1] Univ Fed Pernambuco, Qual Control Core Med & Correlates, Pharmaceut Sci Dept, Recife, PE, Brazil
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2021年 / 193卷
关键词：
Polysaccharides; Sterculia gum; Chemical modifications; Drug delivery systems; KARAYA GUM; ELECTROACTIVE NANOCOMPOSITES; CHEMICAL-COMPOSITION; CONTROLLED-RELEASE; GREEN SYNTHESIS; POLYSACCHARIDE; STRIATA; HYDROGEL; FOETIDA; ANTIBACTERIAL;
D O I：
10.1016/j.ijbiomac.2021.10.145
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Trees of the genus Sterculia produce polysaccharide-rich exudates, such as karaya gum (Sterculia urens), chicha gum (Sterculia striata), and Sterculia foetida gum. These anionic biomaterials are biodegradable, with high vis-cosity, low toxicity, and gelling properties in aqueous media. According to these properties, they show promising applications as a polymer matrix for use in drug delivery systems. For this application, both the chemically modified and the unmodified polysaccharide are used. This review focuses on analyzing the state of the art of recent studies on the use of Sterculia gums in a variety of pharmaceutical forms, such as tablets, hydrogels, micro/ nanoparticles, and mucoadhesive films. Sterculia gums-based delivery systems have potential to be explored for new drug delivery systems.
引用
收藏
页码：481 / 490
页数：10
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