Concentrations of organochlorine pesticides in umbilical cord blood and related lifestyle and dietary intake factors among pregnant women of the Huaihe River Basin in China

被引：34

作者：

Luo, Dan ^{[1
,2
,3
]}

Pu, Yabing ^{[1
,2
,3
]}

Tian, Haoyuan ^{[4
]}

Cheng, Juan ^{[1
,2
,3
]}

Zhou, Tingting ^{[1
,2
,3
]}

Tao, Yun ^{[1
,2
,3
]}

Yuan, Jing ^{[1
,2
,3
]}

Sun, Xin ^{[4
]}

Mei, Surong ^{[1
,2
,3
]}

机构：

[1] Huazhong Univ Sci & Technol, Key Lab Environm & Hlth, Minist Educ, Sch Publ Hlth,Tongji Med Coll, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China

[2] Huazhong Univ Sci & Technol, Minist Environm Protect, Tongji Med Coll, Sch Publ Hlth, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China

[3] Huazhong Univ Sci & Technol, State Key Lab Environm Hlth Incubat, Sch Publ Hlth, Tongji Med Coll, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China

[4] Chinese Ctr Dis Control & Prevent, Key Lab Chem Safety & Hlth, Natl Inst Occupat Hlth & Poison Control, 27 Nan Wei Rd, Beijing 100050, Peoples R China

来源：

ENVIRONMENT INTERNATIONAL | 2016年 / 92-93卷

关键词：

Organochlorine pesticides; Pregnant women; Lifestyle factors; Dietary intake; Umbilical cord blood; Huaihe River Basin; PERSISTENT ORGANIC POLLUTANTS; POLYCHLORINATED-BIPHENYLS; SERUM CONCENTRATIONS; PRENATAL EXPOSURE; BREAST-MILK; SPONTANEOUS-ABORTION; UPPER REACH; ASSOCIATION; RESIDUES; SEDIMENTS;

D O I：

10.1016/j.envint.2016.04.017

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Organochlorine pesticides (OCPs), one of the persistent organic pollutants (POPs) with highly lipophilic properties, long half-lives, and persistence in the environment, are prevalent in the environment even though they have been banned for >30 years. We aimed to investigate the current OCP exposure levels in cord blood from healthy pregnant women residing in the Huaihe River Basin, China, and examined the association between OCP levels and dietary habits and lifestyle factors. In this study, we measured the exposure levels of 17 OCPs in the umbilical cord blood from 999 healthy pregnant women; we also administered 1000 self-reported questionnaires regarding the general characteristics and dietary habits of those women. Our results showed that rho,rho'-DDE, rho,rho'-DDT, aldrin, dieldrin, and methoxychlor, which had higher measured concentrations (2.01 +/- 1.89, 4.31 +/- 5.68, 7.29 +/- 8.74, 5.27 +/- 7.65, and 0.98 +/- 1.42 ng/mL, respectively) and detection frequencies (99.69%, 100.00%, 81.79%, 75.00%, and 74.49%, respectively), were the predominant OCPs in cord blood, and the higher levels of DDTs, aldrin, dieldrin, and methoxychlor were mainly due to recent use. In addition, most of the HCHs in cord blood were derived not only from historical use of technical HCH, but also from the additional use of lindane. In addition, we found that the education level of the pregnant women and monthly household income were positively correlated with OCP levels, particularly rho,rho'-DDE, aldrin, and dieldrin. Furthermore, the consumption of red meat (pork, beef, and lamb), fish, and bean products may be an important contributing factor to the increased concentrations of OCPs in cord blood, while the intake of poultry and pickles was negatively correlated with aldrin level. This study is the first to provide adequate data on current OCP exposure levels in cord blood from pregnant women in the Huaihe River Basin. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：276 / 283

页数：8

共 66 条

[11] In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children [J].