To be or not to be: generation of hepatocytes from cells outside the liver

被引:25
作者
Fox, Ira J. [1 ]
Strom, Stephen C. [2 ]
机构
[1] Univ Nebraska, Med Ctr, Div Transplantat, Dept Surg, Omaha, NE 68182 USA
[2] Univ Pittsburgh, Sch Med, Dept Pathol, Pittsburgh, PA USA
关键词
D O I
10.1053/j.gastro.2008.01.065
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:878 / 881
页数:4
相关论文
共 10 条
[1]   Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells [J].
Campard, David ;
Lysy, Philippe A. ;
Najimi, Mustapha ;
Sokal, E-Fienne Marc .
GASTROENTEROLOGY, 2008, 134 (03) :833-848
[2]   Stem cell characteristics of amniotic epithelial cells [J].
Miki, T ;
Lehmann, T ;
Cai, HB ;
Stolz, DB ;
Strom, SC .
STEM CELLS, 2005, 23 (10) :1549-1559
[3]   Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion [J].
Newsome, PN ;
Johannessen, I ;
Boyle, S ;
Dalakas, E ;
McAulay, KA ;
Samuel, K ;
Rae, F ;
Forrester, L ;
Turner, ML ;
Hayes, PC ;
Harrison, DJ ;
Bickmore, WA ;
Plevris, JN .
GASTROENTEROLOGY, 2003, 124 (07) :1891-1900
[4]   Bone marrow as a potential source of hepatic oval cells [J].
Petersen, BE ;
Bowen, WC ;
Patrene, KD ;
Mars, WM ;
Sullivan, AK ;
Murase, N ;
Boggs, SS ;
Greenberger, JS ;
Goff, JP .
SCIENCE, 1999, 284 (5417) :1168-1170
[5]   Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells [J].
Ruhnke, M ;
Ungefroren, H ;
Nussler, A ;
Martin, F ;
Brulport, M ;
Schormann, W ;
Hengstler, JG ;
Klapper, W ;
Ulrichs, K ;
Hutchinson, JA ;
Soria, B ;
Parwaresch, RM ;
Heeckt, P ;
Kremer, B ;
Fändrich, F .
GASTROENTEROLOGY, 2005, 128 (07) :1774-1786
[6]   Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver [J].
Sharma, AD ;
Cantz, T ;
Richter, R ;
Eckert, K ;
Henschler, R ;
Wilkens, L ;
Jochheim-Richter, A ;
Arseniev, L ;
Ott, M .
AMERICAN JOURNAL OF PATHOLOGY, 2005, 167 (02) :555-564
[7]   Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes [J].
Soto-Gutierrez, Alejandro ;
Kobayashi, Naoya ;
Rivas-Carrillo, Jorge David ;
Navarro-Alvarez, Nalu ;
Zhao, Debaio ;
Okitsu, Teru ;
Noguchi, Hirofumi ;
Basma, Hesham ;
Tabata, Yashuhiko ;
Chen, Yong ;
Tanaka, Kimiaki ;
Narushima, Michiki ;
Miki, Atsushi ;
Ueda, Tadayoshi ;
Jun, Hee-Sook ;
Yoon, Ji-Won ;
Lebkowski, Jane ;
Tanaka, Noriaki ;
Fox, Ira J. .
NATURE BIOTECHNOLOGY, 2006, 24 (11) :1412-1419
[8]   Formation of human hepatocyte-like cells with different cellular phenotypes by human umbilical cord blood-derived cells in the human-rat chimeras [J].
Sun, Yan ;
Xiao, Dong ;
Zhang, Ruo-Shuang ;
Cui, Guang-Hui ;
Wang, Xin-Hua ;
Chen, Xi-Gu .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 357 (04) :1160-1165
[9]   Induction of pluripotent stem cells from adult human fibroblasts by defined factors [J].
Takahashi, Kazutoshi ;
Tanabe, Koji ;
Ohnuki, Mari ;
Narita, Megumi ;
Ichisaka, Tomoko ;
Tomoda, Kiichiro ;
Yamanaka, Shinya .
CELL, 2007, 131 (05) :861-872
[10]   Induced pluripotent stem cell lines derived from human somatic cells [J].
Yu, Junying ;
Vodyanik, Maxim A. ;
Smuga-Otto, Kim ;
Antosiewicz-Bourget, Jessica ;
Frane, Jennifer L. ;
Tian, Shulan ;
Nie, Jeff ;
Jonsdottir, Gudrun A. ;
Ruotti, Victor ;
Stewart, Ron ;
Slukvin, Igor I. ;
Thomson, James A. .
SCIENCE, 2007, 318 (5858) :1917-1920