Current Priorities for Public Health Practice in Addressing the Role of Human Genomics in Improving Population Health

被引:56
作者
Khoury, Muin J. [1 ,2 ]
Bowen, Michael S. [1 ]
Burke, Wylie [3 ]
Coates, Ralph J. [1 ]
Dowling, Nicole F. [1 ]
Evans, James P. [4 ]
Reyes, Michele [1 ]
St Pierre, Jeannette [1 ]
机构
[1] CDC, Off Publ Hlth Genom, Atlanta, GA 30333 USA
[2] NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA
[3] Univ Washington, Dept Bioeth & Humanities, Seattle, WA 98195 USA
[4] Univ N Carolina, Dept Genet, Chapel Hill, NC USA
关键词
GENETIC TESTING STRATEGIES; EGAPP WORKING GROUP; DISEASE PREVENTION; FAMILY-HISTORY; UNITED-STATES; COLORECTAL-CANCER; LYNCH SYNDROME; MEDICINE; HYPERCHOLESTEROLEMIA; RECOMMENDATIONS;
D O I
10.1016/j.amepre.2010.12.009
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In spite of accelerating human genome discoveries in a wide variety of diseases of public health significance, the promise of personalized health care and disease prevention based on genomics has lagged behind. In a time of limited resources, public health agencies must continue to focus on implementing programs that can improve health and prevent disease now. Nevertheless, public health has an important and assertive leadership role in addressing the promise and pitfalls of human genomics for population health. Such efforts are needed not only to implement what is known in genomics to improve health but also to reduce potential harm and create the infrastructure needed to derive health benefits in the future. (Am J Prev Med 2011;40(4):486-493) (C) 2011 Published by Elsevier Inc. on behalf of American Journal of Preventive Medicine.
引用
收藏
页码:486 / 493
页数:8
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