A case of infectious mononucleosis complicated with spontaneous atraumatic splenic rapture caused by Epstein-Barr virus infection

被引:4
作者
Lu, Qiliang [1 ,2 ]
Fu, Wen [1 ,2 ]
Ouyang, Guangxiong [1 ,2 ]
Xu, Qiuran [2 ]
Huang, Dongsheng [2 ]
机构
[1] Qingdao Univ, Qingdao Med Coll, Qingdao, Peoples R China
[2] Zhejiang Prov Peoples Hosp, Key Lab Tumor Mol Diag & Individualized Med Zheji, Affiliated Peoples Hosp, Hangzhou Med Coll, Hangzhou 310000, Peoples R China
基金
中国国家自然科学基金;
关键词
Epstein-Barr virus; infection; splenic rupture; lymphocyte; RUPTURE;
D O I
10.1002/jmv.28083
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Splenic rupture is the most serious complication of infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV) infection, with a mortality rate of over 1 in 10. We reported a case of spontaneous atraumatic splenic rupture secondary to IM in a young man. The patient presented with abdominal pain caused by splenic rupture as the initial symptom. The diagnosis and treatment process went through a series of twists and turns, including the emergency department, general surgery department, and infection department. This case suggests that clinicians should consider the possibility of EBV infection in young patients with spleen rupture without obvious cause to avoid misdiagnosis and missed diagnosis.
引用
收藏
页码:6127 / 6132
页数:6
相关论文
共 21 条
[1]   Ganciclovir and the treatment of Epstein-Barr virus hepatitis [J].
Adams, Leon A. ;
Deboer, Bastiaan ;
Jeffrey, Gary ;
Marley, Richard ;
Garas, George .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2006, 21 (11) :1758-1760
[2]   AVIDITIES OF IGG DIRECTED AGAINST VIRAL CAPSID ANTIGEN OR EARLY ANTIGEN - USEFUL MARKERS FOR SIGNIFICANT EPSTEIN-BARR-VIRUS SEROLOGY [J].
ANDERSSON, A ;
VETTER, V ;
KREUTZER, L ;
BAUER, G .
JOURNAL OF MEDICAL VIROLOGY, 1994, 43 (03) :238-244
[3]  
Asgari MM, 1997, YALE J BIOL MED, V70, P175
[4]   Splenic rupture in infectious mononucleosis: A systematic review of published case reports [J].
Bartlett, A. ;
Williams, R. ;
Hilton, M. .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2016, 47 (03) :531-538
[5]   Incidence of Rash After Amoxicillin Treatment in Children With Infectious Mononucleosis [J].
Chovel-Sella, Aluma ;
Ben Tov, Amir ;
Lahav, Einat ;
Mor, Orna ;
Rudich, Hagit ;
Paret, Gideon ;
Reif, Shimon .
PEDIATRICS, 2013, 131 (05) :E1424-E1427
[6]   Antiviral agents for infectious mononucleosis (glandular fever) [J].
De Paor, Muireann ;
O'Brien, Kirsty ;
Fahey, Tom ;
Smith, Susan M. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2016, (12)
[7]  
De Paschale Massimo, 2012, World J Virol, V1, P31, DOI 10.5501/wjv.v1.i1.31
[8]  
Foreman BH, 2005, J FAM PRACTICE, V54, P547
[9]   Laboratory assays for Epstein-Barr virus-related disease [J].
Gulley, Margaret L. ;
Tang, Weihua .
JOURNAL OF MOLECULAR DIAGNOSTICS, 2008, 10 (04) :279-292
[10]  
Hoagland R J, 1975, Prim Care, V2, P295